Correlated Drug Terms (1)

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	Name (Synonyms)	Correlation
drug2602	Unsupervised physical activities Wiki	1.00

Correlated MeSH Terms (1)

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	Name (Synonyms)	Correlation
D010300	Parkinsonian NIH	0.58

Correlated HPO Terms (0)

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	Name (Synonyms)	Correlation

Primary Outcomes

Description: The quality of life (QoL) will be measured by the Parkinson's Disease Quality of life (PDQ-8). PDQ-8 is a reduced version of a specific health status questionnaire comprising 39 items, with 8 items. Respondents are requested to affirm one of five ordered response categories according to how often, due to their PD, they have experienced the problem defined by each item. Each item is grouped into eight scales that are scored by expressing summed item scores as a percentage score ranging between 0 and 100 (100¼more health problems).

Measure: Quality of life (QoL)

Time: Change from baseline at 12 weeks.

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Description: This outcome will be measure for the Geriatric Depression Scale - 15 item. The scale consists of 15 dichotomous questions in which participants are asked to answer yes or no about how they felt over the past week (for instance, "Do the patient feel that their life is empty?," Do the patient feel that their situation is hopeless?). Scores range from 0 to 15 with higher scores indicating more depressive symptoms.

Measure: Depressive symptoms - Geriatric Depression Scale - 15 item

Time: Change from baseline at 12 weeks.

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Description: This outcome will be measure for the International Physical Activity Questionnaires (IPAQ). The IPAQ comprises a set of 4 questionnaires. Long (5 activity domains asked independently) and short (4 generic items) versions for use by either telephone or self-administered methods are available. The purpose of the questionnaires is to provide common instruments that can be used to obtain internationally comparable data on health-related physical activity.

Measure: Physical Activity - International Physical Activity Questionnaires (IPAQ)

Time: Change from baseline at 12 weeks.

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Secondary Outcomes

Description: Montreal Cognitive Assessment (MoCA) is a brief screening tool for mild cognitive impairment. This evaluation accesses different cognitive domains and investigates the individual's abilities in the following areas: attention and concentration, executive functions, memory, language, visuoconstructive skills, conceptualization, calculation, and orientation. The total score of the MoCA is 30 points, with a score of 26, or more, considered normal and less than 26 is considered a cognitive impairment.

Measure: Cognitive function - Montreal Cognitive Assessment by telephone

Time: Change from baseline at 12 weeks.

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Description: This outcome will be measure for the Falls - Falls Efficacy Scale - International (FES-I). FES-I can be administered as self-completion questionnaires, or administered verbally as part of a research interview or clinical assessment. To calculate the FES-I score when all items are completed, simply add the scores for each item together to give a total that ranges as follows: minimum 16 (no concern about falling) to maximum 64 (severe concern about falling).

Measure: Falls - Falls Efficacy Scale - International

Time: Change from baseline at 12 weeks.

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Description: The Five Times Sit to Stand Test measures one aspect of transfer skill. This test quantifies functional lower extremity strength and identifies movement strategies a people use to complete the transitional movement.

Measure: Functional lower extremity strength -Five Times Sit to Stand Test

Time: Change from baseline at 12 weeks.

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