CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

Colchicine 1 MG Oral TabletWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)

Name (Synonyms) Correlation
drug1056 High Intensity Resistance (HIT-RT) and Endurance exercise (HIIT) Wiki 1.00
drug2692 Wellness Wiki 1.00

Correlated MeSH Terms (1)

Name (Synonyms) Correlation
D001851 Bone Diseases, Metabolic NIH 1.00

Correlated HPO Terms (1)

Name (Synonyms) Correlation
HP:0000938 Osteopenia HPO 1.00

There is one clinical trial.

Clinical Trials

1 Treatment With COLchicine of Patients Affected by COVID-19: a Pilot Study

This is an interventional, pilot, multicenter, randomized, open-label, phase 2 study, enrolling patients with COVID-19 disease. One-month rate of entering the critical stage (either a. Respiratory failure occurs and requires mechanical ventilation; b. Patients combined with other organ failure need ICU monitoring and treatment; c. Death) is the primary endpoint.

NCT04375202 COVID-19 Drug: Colchicine 1 MG Oral Tablet

Primary Outcomes

Description: Comply with any of the followings: Respiratory failure occurs and requires mechanical ventilation; Patients combined with other organ failure need ICU monitoring and treatment Death

Measure: Rate of entering the critical stage

Time: [1 month]

Secondary Outcomes

Measure: Trend of White blood cell count

Time: [up to 30 days]

Measure: Change of the "Sequential Organ failure Assessment" (SOFA)

Time: [up to 30 days]

Measure: Rate of biochemical criterion (CK, ALT, ferritin) recovery

Time: [up to 30 days]

Description: Comply with any of the followings: No fever, cough and other symptoms; SPO2>94% or PaO2/FiO2 >350mmHg without oxygen inhalation

Measure: Rate of disease remission

Time: [up to 30 days]

Description: Rate of adverse events codified by Common Terminology Criteria for Adverse Events (CTCAE) v5.0

Measure: Toxicity of Colchicine

Time: [up to 30 days]

No related HPO nodes (Using clinical trials)