CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


olfactory deviceWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


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Name (Synonyms) Correlation
drug681 Covidfree@home Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D018352 Coronavirus Infections NIH 0.04

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Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Validation of a Rapid Quantitative Test for Loss of Smell in COVID-19 Subjects

The purpose of this study is to evaluate the performance of a non-invasive olfactory device as a rapid indicator of COVID-19 in positive subjects.

NCT04431908 COVID-19 Device: olfactory device

Primary Outcomes

Description: The subject's score on using the olfactory device will be compared to the PCR results (SARS-CoV-2 negative or positive) on COVID19 outpatients. As the smell test has a variable scale (0-5) the ideal cutoff will be determined to maximize these factors: Sensitivity Specificity Accuracy

Measure: sensitivity, specificity and accuracy

Time: 24 hours

Secondary Outcomes

Description: Repeatability will also be examined in a test-retest score conducted within 24 hours with a second device in which the sequence of the odorants is altered.

Measure: repeatability

Time: 48 hours

Description: The score with the olfactory device will also be compared to subjects' response to the question "Do you have a new loss of smell or taste?" (current standard).

Measure: validation

Time: 24 hours

Description: We will determine if 'asymptomatic' SARS-CoV-2 positive subjects experience a partial loss of smell (hyposmia) and if so determine the fraction of subjects in which this occurs. Sensitivity, specificity and accuracy will be measured.

Measure: asymptomatic sensitivity, specificity and accuracy

Time: 24 hours


No related HPO nodes (Using clinical trials)