CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

pre_dinner Yoga-based breathing supportWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)

Name (Synonyms) Correlation
drug2961 pre_lunch Yoga-based breathing support Wiki 1.00
drug2899 morning Yoga-based breathing support Wiki 1.00
drug2649 Virtual ACT Workshop for Emotional Eating Wiki 1.00

Correlated MeSH Terms (4)

Name (Synonyms) Correlation
D011618 Psychotic Disorders NIH 0.50
D001523 Mental Disorders NIH 0.21
D045169 Severe Acute Respiratory Syndrome NIH 0.05
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (1)

Name (Synonyms) Correlation
HP:0000709 Psychosis HPO 0.50

There is one clinical trial.

Clinical Trials

1 Yoga- Based Breathing for Vagus Nerve Stimulation as Home-care Adjuvant Treatment Against Burden COVID-19

COronaVIrus Disease or Severe Acute Respiratory Syndrome -CoV-2 or COVID-19, mortality occurs mainly from immunological behavior or by suicide after healing . In both cases, the causal link is coronavirus within the host response. The rationale of use of deep yoga breathing as adjuvant treatment to COVID-19 disease , is linked to the mechanical action to stimulate the vagus nerve through scalene and sternocleidomastoid muscles function of which the continuity of action bring to modulate upto suppress, the inflammatory reflex and pro-inflammatory cytokines overproduction and contextual lowering of the sympathetic stress response as a first cause of sleep and late mental disorders which can increase the annual suicide rate. An easily breathing medical Yoga protocol has been developed to test a cost-effective care provision, training, contact tracing and mass efficacy testing.

NCT04413747 Coronavirus Infection Cytokine Storm Mental Disorder Behavioral: morning Yoga-based breathing support Behavioral: pre_lunch Yoga-based breathing support Behavioral: pre_dinner Yoga-based breathing support
MeSH:Coronavirus Infections Severe Acute Respiratory Syndrome Mental Disorders Psychotic Disorders
HPO:Psychosis

Primary Outcomes

Description: COVID-19's Patients mortality all cause: incidence proportion.

Measure: Mortality

Time: 12 months.

Description: COVID-19's Patients suicide: incidence proportion.

Measure: Mortality-suicide

Time: 12 months.

Secondary Outcomes

Description: In-hospital COVID-19's Patients oxygen invasive ventilation or high flow oxygen devices :incidence proportion of Brescia COVID-19 respiratory Severity Scale Index (Levels 0-3 worse outcome) cutoff Level ≥ 2 -

Measure: Incidence of hospitalization for respiratory failure of COVID-19's Patients-

Time: 1 months.

Description: Homecare interventions for anxiety and depression requiring drugs treatment: incidence proportion.

Measure: Incidence of al home professional psychiatric-psychological interventions for mental disorder.

Time: 12 months.

Description: Scoring system for depression and anxiety requiring drugs treatment: incidence proportion of BDI-II aggregate components score 0- 63 ( worse outcome) , cutoff > 29.

Measure: Incidence of mental disorder: Beck Depression Inventory-Second Edition (BDI-II).

Time: 12 months.

Description: Scoring system for sleep disorders requiring drugs treatment: incidence proportion of aggregate PSQI score 0-21 (worse outcome) , cutoff > 8.

Measure: Incidence od spleep disorder:Pittsburgh Sleep Quality Index (PSQI).

Time: 12 months.

Related HPO nodes (Using clinical trials)

HP:0000709: Psychosis
Genes 115
MKRN3-AS1 ALAD PDGFRB C9ORF72 SH2B1 TTC19 FCGR2B SLC25A13 CTLA4 ACADS MYORG HFE PDGFB GRN PRDM8 CACNA1A TRNF SOBP UPF3B GSS ALDH5A1 SNRPN PWAR1 STAT4 TBC1D7 ZFYVE26 MECP2 CBS EPM2A MED12 ATP13A2 ND1 ND4 PDGFB USP8 SLC6A19 CDH23 VPS13A COX1 SPART SQSTM1 TWNK ITM2B TRNW NPAP1 MKRN3 TRNQ DNMT1 ND5 PRKAR1A ABCD1 GCLC SLC7A7 IRAK1 PRNP CLN8 ND6 PCDH19 PPOX NPC2 SLC12A6 SNORD116-1 PARK7 ATXN7 MAPT SLC20A2 PAK3 NDP COX3 HMBS KCNT1 WFS1 DNASE1 AIP TMEM106B ALDH18A1 PCDH19 PWRN1 PSEN1 NDN COX2 C9ORF72 RPS6KA3 PDE11A TRNS2 WFS1 TREM2 NDP CHMP2B PUS3 PTPN22 SPP1 IPW DCAF17 DCAF17 LMBRD1 HERC2 ZDHHC9 TREX1 CLN3 NHLRC1 TRNS1 MAGEL2 PANK2 GNAS TRNL1 FCGR2A TRNH VCP NAGS USP8 SNORD115-1 NPC1 MED12 PAH
Protein Mutations 6
D61804R N40D S311C S9G V158M V66M
SNP 4
rs1006737 rs1799732 rs3813929 rs6971