CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

MCN (Methylene blue, vitamin C, N-acetyl cysteine)Wiki

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Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)

Name (Synonyms) Correlation
drug2949 pirfenidone Wiki 1.00

Correlated MeSH Terms (3)

Name (Synonyms) Correlation
D011014 Pneumonia NIH 0.06
D045169 Severe Acute Respiratory Syndrome NIH 0.05
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (1)

Name (Synonyms) Correlation
HP:0002090 Pneumonia HPO 0.06

There is one clinical trial.

Clinical Trials

1 The Clinical Trial of Application of Methylene Blue Vial for Treatment of Covid-19 Patients

The severe acute respiratory syndrome caused by COVID-19 is now a global catastrophic event. Currently there is no approved drug or vaccine for the disease. Methylene blue (MB, oxidized form, blue color) has been used in many different areas of clinical medicine, ranging from malaria to orthopedics. Leucomethylene Blue (reduced form of MB, colorless) may be applied for the treatment of COVID-19 according to the scientific evidences.

NCT04370288 Covid-19 Drug: MCN (Methylene blue, vitamin C, N-acetyl cysteine)

Primary Outcomes

Description: All patient will be assess for changes in disease severity.

Measure: Proportion of patients remaining free of need for mechanical ventilation in both groups

Time: Day 7

Secondary Outcomes

Measure: Mortality rate in both groups

Time: Day 28

Measure: Improvement in Pa02/Fi02 ratio in both groups

Time: Day 2

Measure: Duration of hospital stay in both group.

Time: Day 28

Measure: Duration of Intensive Care Unit stay in both groups

Time: Day 28

Measure: Days free of dialysis in both groups

Time: Day 28

Measure: C-reactive proteins

Time: 3-5 Days

Measure: WBC Count

Time: 3-5 Days

No related HPO nodes (Using clinical trials)