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Danoprevir+RitonavirWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (0)


Name (Synonyms) Correlation

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D007239 Infection NIH 0.06

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 An Open Clinical Trial to Evaluate Danoprevir Sodium Tablets Combined With Ritonavir in the Treatment of SARS-CoV-2 Infection

Evaluation of the efficacy and safety of Danoprevir sodium tablet combined with ritonavir for SARS-CoV-2 infected patients.

NCT04345276 COVID-19 Drug: Danoprevir+Ritonavir
MeSH:Infection

Primary Outcomes

Description: Defined as SPO2≤ 93% without oxygen supplementation, PaO2/FiO2 ≤ 300mmHg or a respiratory rate ≥30 breaths per min without supplemental oxygen min without supplemental oxygen

Measure: Rate of composite adverse outcomes

Time: Within 10 days after administration

Secondary Outcomes

Description: Clinical recovery was defined as sustained (48 hours) alleviation of illness based on symptom scores (fever, cough, diarrhea, myalgia, dyspnea) all being absent and no evidence for progression (newly-presented dyspnea, SpO2 decline ≥3%, respiratory rate ≥ 30 breaths per min without supplemental oxygen).

Measure: Time to recovery

Time: Within 10 days after administration

Measure: Rate of no fever

Time: Within 10 days after administration

Measure: Rate of no cough

Time: Within 10 days after administration

Measure: Rate of no dyspnea

Time: Within 10 days after administration

Measure: Rate of no requiring supplemental oxygen

Time: Within 10 days after administration

Measure: Rate of undetectable New coronavirus pathogen nucleic acid

Time: Within 10 days after administration

Measure: Rate of mechanical ventilation

Time: Within 10 days after administration

Measure: Rate of ICU admission

Time: Within 10 days after administration

Measure: Rate of serious adverse event

Time: Within 10 days after administration


No related HPO nodes (Using clinical trials)