CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Placebo (Methylcellulose) capsuleWiki

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Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug1462 Melatonin Wiki 0.71

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 A Pilot Placebo-controlled Randomized Double-blind Trial of Melatonin in Outpatients With COVID-19 Infection

This study is a pilot randomized, double-blind, placebo-controlled clinical trial to evaluate the safety and efficacy of melatonin in adult outpatients suspected to be afflicted with COVID-19.

NCT04474483 COVID-19 Drug: Melatonin Other: Placebo (Methylcellulose) capsule

Primary Outcomes

Description: Evaluate the incidence of serious adverse effects and discontinuation secondary to toxicity through 28 days of follow-up as compared to the control arm as assessed by: Cumulative incidence of serious adverse events (SAEs), Cumulative incidence of Grade 3 and 4 adverse events (AEs), Discontinuation or temporary suspension of the investigational medication (for any reason).

Measure: Cumulative Incidence of Treatment-Emergent Adverse Events

Time: 28 days

Secondary Outcomes

Description: Incidence of COVID-19 related hospitalization at 28 days

Measure: Hospitalization

Time: 28 days

Description: COVID-19 related symptoms (Fever, chills, cough, nasal symptoms, body aches/muscle aches, headache, loss of smell, loss of taste, nausea, vomiting, diarrhea, fatigue, dizziness) that are self-reported and on interview.

Measure: COVID-19 related symptoms

Time: 28 days

Description: Change from baseline (day 1) as assessed to days 3, 7, 14, and 28

Measure: Rate of resolution of COVID-19 related symptoms

Time: 28 days

Description: 28-day mortality

Measure: Mortality

Time: 28 days


No related HPO nodes (Using clinical trials)