CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


CT-ScanWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug2545 Traditional antirheumatic drugs Wiki 0.71

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D001171 Arthritis, Juvenile NIH 0.71
D001168 Arthritis NIH 0.41
D001172 Arthritis, Rheumatoid NIH 0.27

Correlated HPO Terms (2)


Name (Synonyms) Correlation
HP:0001369 Arthritis HPO 0.41
HP:0001370 Rheumatoid arthritis HPO 0.27

There are 2 clinical trials

Clinical Trials


1 Prediction of Clinical Course in COVID19 Patients Using Unsupervised Classification Approaches of Clinical, Biological and the Multiparametric Signature of the Chest CT Scan Performed at Admission

In the context of the COVID19 pandemic and containment, chest CT is currently frequently performed on admission, looking for suggestive signs and basic abnormalities of COVID19 compatible viral pneumonitis pending confirmation of identification of viral RNA by reverse-transcription polymerase chain reaction(PCR), with a reported sensitivity of 56-88% in the first few days, slightly higher than PCR (60%) (1). Nevertheless, currently established radiological abnormalities are not specific for COVID19 and the specificity of the chest CT is ~25% when PCR is used as a reference (1). Deconfinement and its consequences will complicate the triage of COVID patients and the role of the scanner, with the expected impact of a decrease in the prevalence of infection in the emergency department and an increase in the number of "all-round" patients, including patients with non-COVID viral infiltrates or pneumopathies. In addition, there are currently no imaging criteria to complement the clinical and biological data that can predict the progression of lung disease from the initial data.

NCT04377685 COVID 19 Other: CT-Scan

Primary Outcomes

Description: The diagnostoc of COVID disease is composite of: CT features wich will include presence/location/laterality of morphological CT abonormal densities (ground glass opacities, consolidations, reticulations), pulmonary vessels size, distribution and abnormalities, local / global CT-ventilation index (CT-VI) severity, radiomic features (shape features, 1st-order and 2nd order statistics) Analysis of CT-Scan results.

Measure: diagnostic of COVID disease composite

Time: On admission to the hospital

2 Initial Thoracic CT Findings and Mechanical Ventilation Requirement in Patients Admitted to Intensive Care Unit With COVID-19

The most common thorax Computed tomography (CT) findings are multifocal ground-glass opacities and peripheral consolidation in patients with COVID-19. Septal thickening, bronchiectasis, pleural thickening, and subpleural involvement may also be observed. Although these findings are not specific to COVID-19, the severity of pulmonary involvement is expected to be correlated with thorax CT findings.

NCT04424849 COVID-19 Diagnostic Test: CT-Scan

Primary Outcomes

Description: Whether Thorax CT findings predict invasive mechanical ventilation requirement of covid-19 patients

Measure: Invasive respiratory support in patients with COVID-19

Time: 120 days

Secondary Outcomes

Description: Whether Thorax CT findings predict mortality of covid-19 patients

Measure: Mortality in patients with COVID-19

Time: 120 days


No related HPO nodes (Using clinical trials)