CovidResearchTrials by Shray Alag


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Mesenchymal stem cellsWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug2067 Remdesivir Wiki 0.26
drug1822 Placebo Wiki 0.06

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Prospective, Randomized Phase 2 Clinical Trial of Mesenchymal Stem Cells(MSCs) for the Treatment of Coronavirus Disease 2019(COVID-19)

Since the outbreak of coronavirusdisease2019(COVID-19), many researchers in China have carried out/published clinical trials on treatment based on Western medicine, traditional Chinese medicine or a combination of the two. Trials on treatment modalities have mainly used antivirals, interferon, glucocorticoids in addition to traditional Chinese medicine. There are also clinical trials exploring hydroxyquinoline/chloroquine sulphate, immunoglobulins, Vitamin-C, washed microbiota, nebulized interferon, teicoplanin as well as Mesenchymal stem cells. However, most of these trials were small (median sample size 100) and the bulk of potential therapeutic strategies remain in the experimental phase and currently there is no effective specific antiviral with high-level evidence.The aim of this study is assess the efficacy of MSCs as an add-on therapy to standard supportive treatment for patients with moderate/severe COVID-19.

NCT04444271 COVID-19 Drug: Mesenchymal stem cells Other: Placebo

Primary Outcomes

Description: Assessment of Overall survival at 30 days post intervention

Measure: Overall survival

Time: 30 days post intervention

Secondary Outcomes

Description: days required for oxygen support independence after intervention

Measure: Clinical improvement

Time: 30 days

Description: PCR testing to check PCR negativity

Measure: Time of COVID19 PCR negativity

Time: day 1,3,7,10, 14

Description: Computed tomography Chest assesment will be done to assess improvment in radiological findings of COVID-19

Measure: Radiological improvement (day 15 and day 30 assessment)

Time: day 15 and day30

Description: number of days required for discharge from hospital

Measure: days required to discharge from hospital

Time: 30 days post admission


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