Covid 19 Research using Clinical Trials (Home Page)
(Standard of Care) SoCWiki
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (3)
Correlated MeSH Terms (5)
|
Name (Synonyms) |
Correlation |
D055371 | Acute Lung Injury NIH | 0.10 |
D012127 | Respiratory Distress Syndrome, Newborn NIH | 0.10 |
D012128 | Respiratory Distress Syndrome, Adult NIH | 0.09 |
D045169 | Severe Acute Respiratory Syndrome NIH | 0.05 |
D018352 | Coronavirus Infections NIH | 0.04 |
Correlated HPO Terms (0)
|
Name (Synonyms) |
Correlation |
There is one clinical trial.
Clinical Trials
The (World Health Organization) WHO NOR- (Coronavirus infectious disease) COVID 19 study is a
multi-centre, adaptive, randomized, open clinical trial to evaluate the safety and efficacy
of hydroxychloroquine, remdesivir and standard of care in hospitalized adult patients
diagnosed with COVID-19. This trial will follow the core WHO protocol but has additional
efficacy, safety and explorative endpoints.
Primary Outcomes
Description: All cause in-hospital mortality
Measure: In-hospital mortality
Time: 3 weeks
Secondary Outcomes
Measure: Occurrence and duration of mechanical ventilation Time: 3 weeks
Measure: Occurrence and duration of intensive care unit (ICU) treatment Time: 3 weeks
Measure: Duration of hospital admittance Time: 1 month
Measure: 28 Day mortality Time: 3 weeks
Measure: Viral clearance as assessed by SARS-CoV-2 PCR in peripheral blood and nasopharyngeal airway speciemen Time: 3 weeks
Measure: Occurrence of co-infections Time: 3 weeks
Measure: Occurrence of organ dysfunction Time: 3 months
Other Outcomes
Measure: Inflammatory and anti-inflammatory mediators as assessed in serum and plasma Time: Throughout hospitalization
Measure: Markers of extracellular matrix remodeling Time: Throughout hospitalization and 3 months after remission
Measure: Markers of endothelial activation Time: Throughout hospitalization
Measure: Markers of platelet activation Time: Throughout hospitalization
No related HPO nodes (Using clinical trials)