CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Standardised questionnairesWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug2793 covid-19 positive pregnant women Wiki 1.00
drug387 Blood test Wiki 0.71

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D019052 Depression, Postpartum NIH 0.45
D001008 Anxiety Disorders NIH 0.17
D003863 Depression, NIH 0.15

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 COVID-19 Staff Testing of Antibody Responses Study (CO-STARS)

This study will perform prospective repeated serological antibody testing on a cohort of at least 1000 healthcare workers at Great Ormond Street Hospital. Within this cohort, a subset of 150-250 staff members with confirmed (PCR positive) SARS-CoV-2 disease will be followed with intensive monthly testing for 6 months to determine whether antibody levels in the blood are maintained or decrease during this time. All 1000 recruited healthcare workers will be followed 6-monthly

NCT04380896 SARS-CoV-2 Infection Other: Blood test Other: Standardised questionnaires

Primary Outcomes

Description: To determine the kinetics (rate of change) of SARS-CoV-2 nucleo-capsid protein antibody titres in proven cases of SARS-CoV-2 over the 6 month period following infection

Measure: Change in serial monthly log-transformed antibody titre levels as measured

Time: 6 months period post infection

Secondary Outcomes

Description: To determine the proportion of completely asymptomatic healthcare workers who have evidence of SARS-CoV-2 antibodies in their serum indicative of past infection

Measure: Proportion of completely asymptomatic healthcare workers with evidence of SARS-CoV-2 antibodies

Time: 12 months

Description: To determine the attack rate of SARS-CoV-2 in healthcare workers who have antibodies versus those who do not have antibodies

Measure: The attack rate of SARS-CoV-2 in healthcare workers who have antibodies compared to those who do not

Time: Betwen 3 to 6 years

Description: To determine the immune correlates of protection (Antibody Titres sufficient for protection) against future exposure to SARS-CoV-2

Measure: The immune correlates of protection against future exposure to SARS-CoV-2

Time: Between 3 to 6 years


No related HPO nodes (Using clinical trials)