Name (Synonyms) | Correlation | |
---|---|---|
drug1392 | Lower-dose prophylactic anticoagulation Wiki | 1.00 |
drug2193 | Sampling (EDTA blood, pharyngeal and nose swabs, bronchoalveolar lavage ,urine) Wiki | 1.00 |
Name (Synonyms) | Correlation | |
---|---|---|
D060085 | Coinfection NIH | 0.71 |
D045169 | Severe Acute Respiratory Syndrome NIH | 0.05 |
D018352 | Coronavirus Infections NIH | 0.04 |
Name (Synonyms) | Correlation |
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There is one clinical trial.
This is a randomized open label trial to compare effectiveness of two dosing regimens currently used for prevention of clotting events in COVID-19 positive inpatients. Both doses and routes of anticoagulation regimens are currently used in COVID-19 positive inpatients at NYU Langone Health.
Description: 0 = Uninfected; no viral RNA detected Ambulatory = Asymptomatic; viral RNA detected = Symptomatic: Independent = Symptomatic: assistance needed Hospitalized: Mild disease = Hospitalized; no oxygen therapy = Hospitalized; oxygen by mask or nasal prongs = Hospitalized; oxygen by NIV or High flow = Intubation & Mechanical ventilation, pO2/FIO2 >/= 150 or SpO2/FIO2 = Mechanical ventilation pO2/FIO2 < 150 (SpO2/FIO2 <200) 9 = Mechanical ventilation pO2/FIO2 < 150 and vasopressors, dialysis 10 = Dead N (%)
Measure: Score on WHO Ordinal Scale Time: 30 daysDescription: AKI is defined as any of the following (Not Graded): Increase in SCr by X0.3 mg/dl (X26.5 lmol/l) within 48 hours; or Increase in SCr to X1.5 times baseline, which is known or presumed to have occurred within the prior 7 days; or- Urine volume o0.5 ml/kg/h for 6 hours.
Measure: Incidence of acute kidney injury (KDIGO criteria for Acute Kidney Injury (AKI)) Time: 30 daysDescription: Measured by troponin and NTproBNPlevels
Measure: Cardiac injury Time: 30 daysDescription: measured by D-dimer and fibrinogen levels
Measure: Hypercoagulability Time: 30 daysDescription: Platelet Count >100 x 109/L 0 Points >50 - <100 x 109/L 1 Point <50 x 109/L 2 Points Increase in Fibrin-related Markers [D Dimers] No change 0 Points Moderate rise 2 Points Strong rise 3 Points Prothrombin Time [PT] Prolongation 3 s or less 0 Points >3 s but <6 s 1 Point >6 s 2 Points Fibrinogen [Clauss] Level >1.0 g/L 0 Points <1.0 g/L 1 Point Score 0-8 Interpretation of Score < 5 Suggestive of non-overt/low grade DIC. Repeat in 1-2 days. ≥ 5 Laboratory evidence consistent with overt DIC.
Measure: Disseminated Intravascular Coagulation (DIC) Score Time: 30 days