CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Standard 12-lead ECG, NT-proBNP, echocardiographyWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (0)


Name (Synonyms) Correlation

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D018754 Ventricular Dysfunction NIH 0.71
D018487 Ventricular Dysfunction, Left NIH 0.71

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Opportunistic Screening for Asymptomatic Left Ventricular Dysfunction in COVID-19 Survivors

Coronavirus Disease 2019 (COVID-19) emerged in December 2019, and in mere few months has resulted in a pandemic of viral pneumonia. Substantial proportion of patients with COVID-19 have biochemical evidence of myocardial injuries during the acute phase. Possible mechanisms including acute coronary events, cytokine storm, and COVID-19 related myocarditis, have been postulated for the cardiac involvement in COVID-19. It is uncertain whether COVID-19 survivors are at risk cardiac dysfunction including cardiac arrhythmia and heart failure. The prospective screening study aims to evaluate the possible latent effects from COVID-19 in COVID-19 survivors. COVID-19 survivors 4-6 weeks after hospital discharge will be recruited from the Infectious Disease clinic, Queen Mary Hospital with standard 12-lead electrocardiogram, serum troponin, NT-proBNP, and standard transthoracic echocardiogram. The outcome measures include (1) new onset cardiac arrhythmia, (2) N Terminal (NT)-proBNP elevation above the diagnostic range of heart failure, and (3) newly detected left ventricular dysfunction.

NCT04355884 COVID-19 Diagnostic Test: Standard 12-lead ECG, NT-proBNP, echocardiography
MeSH:Ventricular Dysfunction Ventricular Dysfunction, Left

Primary Outcomes

Description: Atrial fibrillation, conduction block

Measure: New-onset cardiac arrhythmia

Time: At the time of screening

Description: Elevated NT-proBNP level above the age-specific diagnostic threshold of heart failure

Measure: Elevation of NT-proBNP

Time: At the time of screening

Description: Left ventricular systolic function

Measure: Left ventricular dysfunction

Time: At the time of screening


No related HPO nodes (Using clinical trials)