CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Nigella sativaWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug358 Biomarkers expression Wiki 1.00

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D007239 Infection NIH 0.06
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Effects of Nigella Sativa as a Treatment of Patients With Upper Respiratory Tract Infection Caused by SARS-coronavirus-2: a Prospective, Randomized, Open-label, Controlled Clinical Study

Natural products with immunomodulation and antiviral activity showed a promising improvement in the outcomes of some viral infectious diseases both in preclinical and primitive clinical studies. The aim of this study is to utilize Saudi FDA licensed Nigella sativa (NS) seed oil towards improving disease outcomes in hospitalized adult patients diagnosed with COVID-19. The study will be a prospective, open-label, non-randomized controlled pilot trial. Patients will be supplemented (add-on) with one capsule of black seed oil twice daily for 10 days. The primary outcome will be the proportion of patients who clinically recovered on day 14. The secondary outcomes will be clinical parameters and routine laboratory tests. If encouraging outcomes occurred, NS supplementation may be recommended as an add-on to standard care protocol to enhance the recovery from COVID-19 disease in the current emerging situation.

NCT04401202 COVID-19 SARS-CoV-2 Dietary Supplement: Nigella sativa

Primary Outcomes

Measure: Proportion of patients who are clinically recovered

Time: Day 14

Secondary Outcomes

Measure: Time to full clinical recovery or progression to pneumonia or hypoxia

Time: Day 14

Measure: Normalization of chest radiograph

Time: Day 14

Measure: Rate of complications

Time: Day 14

Measure: Death

Time: Day 14


No related HPO nodes (Using clinical trials)