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faecal sample collectorWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


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Name (Synonyms) Correlation

Correlated MeSH Terms (1)

Name (Synonyms) Correlation
D013313 Stress Disorders, Post-Traumatic NIH 0.20

Correlated HPO Terms (0)

Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials

1 Alterations of Gut Microbiome in the Frontline Medical Staff Under the Stress of Fighting Against 2019-nCoV

With the outbreak of 2019 novel coronavirus (2019-nCoV), the frontline medical workers faced enormous stress, including a high risk of infection and inadequate protection from contamination, isolation, patients with negative emotions, a lack of contact with their families, and exhaustion, which may cause mental health problems. The investigators plan to collect the faecal samples and clinical assessments from a part of frontline medical workers in three time points to analyse the changing profile of gut microbiome according to outcomes of 16s rRNA sequencing. The samples from the matched health controls will also be sequenced to compare with the exposed group in gut microbiome community.

NCT04443075 Stress Disorders, Post-Traumatic Device: faecal sample collector
MeSH:Stress Disorders, Post-Traumatic

Primary Outcomes

Description: Gut microbiome composition will be anaylysed using 16S rRNA sequencing.

Measure: Gut microbiome composition of exposed group

Time: immediately after the frontline workers come back to Xi'an

Description: Gut microbiome composition will be anaylysed using 16S rRNA sequencing.

Measure: Gut microbiome composition of exposed group

Time: immediately after the frontline workers isolated for two weeks

Description: Gut microbiome composition will be anaylysed using 16S rRNA sequencing.

Measure: Gut microbiome composition of exposed group

Time: immediately after the frontline workers going back to normal work for one month

Description: Gut microbiome composition will be anaylysed using 16S rRNA sequencing.

Measure: Gut microbiome composition of non-exposed group

Time: During the procedure of collecting faecal samples from exposed group

Description: It's a self-report measure assessing subjective distress resulting from a traumatic life event, with a total score of 0-88. Higher score means a worse outcome

Measure: The Impact of Event Scale-Revised (IES-R) of exposed group

Time: immediately after the frontline workers come back to Xi'an

Description: It's a self-report measure assessing subjective distress resulting from a traumatic life event, with a total score of 0-88. Higher score means a worse outcome

Measure: The Impact of Event Scale-Revised (IES-R) of exposed group

Time: immediately after the frontline workers isolated for two weeks

Description: It's a self-report measure assessing subjective distress resulting from a traumatic life event, with a total score of 0-88. Higher score means a worse outcome

Measure: The Impact of Event Scale-Revised (IES-R) of exposed group

Time: immediately after the frontline workers going back to normal work for one month

Description: It's a self-report measure assessing subjective distress resulting from a traumatic life event, with a total score of 0-88. Higher score means a worse outcome

Measure: The Impact of Event Scale-Revised (IES-R) of non-exposed group

Time: During the procedure of collecting faecal samples from non-exposed group

Secondary Outcomes

Description: It's a self-administered measure assessing subjective common mental health with a total score of 0-30. Higher score means a worse outcome.

Measure: The 15-item Patient Health Questionnaire (PHQ-15) of exposed group

Time: immediately after the frontline workers come back to Xi'an

Description: It's a self-administered measure assessing subjective common mental health with a total score of 0-30. Higher score means a worse outcome.

Measure: The 15-item Patient Health Questionnaire (PHQ-15) of exposed group

Time: immediately after the frontline workers isolated for two weeks

Description: It's a self-administered measure assessing subjective common mental health with a total score of 0-30. Higher score means a worse outcome.

Measure: The 15-item Patient Health Questionnaire (PHQ-15) of exposed group

Time: immediately after the frontline workers going back to normal work for one month

Description: It's a self-administered measure assessing subjective common mental health with a total score of 0-30. Higher score means a worse outcome.

Measure: The 15-item Patient Health Questionnaire-15 (PHQ-15) of non-exposed group

Time: During the procedure of collecting faecal samples from non-exposed group

Description: It's a self-report measure widely used for major depression screening with a total score of 0-27. Higher score means a worse outcome.

Measure: The 9-item Patient Health Questionnaire (PHQ-9) of exposed group

Time: immediately after the frontline workers come back to Xi'an

Description: It's a self-report measure widely used for major depression screening with a total score of 0-27. Higher score means a worse outcome.

Measure: The 9-item Patient Health Questionnaire (PHQ-9) of exposed group

Time: immediately after the frontline workers isolated for two weeks

Description: It's a self-report measure widely used for major depression screening with a total score of 0-27. Higher score means a worse outcome.

Measure: The 9-item Patient Health Questionnaire (PHQ-9) of exposed group

Time: immediately after the frontline workers going back to normal work for one month

Description: It's a self-report measure widely used for major depression screening with a total score of 0-27. Higher score means a worse outcome.

Measure: The 9-item Patient Health Questionnaire (PHQ-9) of non-exposed group

Time: During the procedure of collecting faecal samples from non-exposed group

Description: It is a practical self-report anxiety questionnaire with a total score of 0-21. Higher score means a worse outcome.

Measure: The 7-item Generalized Anxiety Disorder Scale (GAD-7) of exposed group

Time: immediately after the frontline workers come back to Xi'an

Description: It is a practical self-report anxiety questionnaire with a total score of 0-21. Higher score means a worse outcome.

Measure: The 7-item Generalized Anxiety Disorder Scale (GAD-7) of exposed group

Time: immediately after the frontline workers isolated for two weeks

Description: It is a practical self-report anxiety questionnaire with a total score of 0-21. Higher score means a worse outcome.

Measure: The 7-item Generalized Anxiety Disorder Scale (GAD-7) of exposed group

Time: immediately after the frontline workers going back to normal work for one month

Description: It is a practical self-report anxiety questionnaire with a total score of 0-21. Higher score means a worse outcome.

Measure: The 7-item Generalized Anxiety Disorder Scale (GAD-7) of non-exposed group

Time: During the procedure of collecting faecal samples from non-exposed group

Description: It is a self-report questionnaire that is widely used to assess several dimensions of sleep with a total score of 0-21. Higher score means a worse outcome

Measure: The Pittsburgh Sleep Quality Index (PSQI) of exposed group

Time: immediately after the frontline workers come back to Xi'an

Description: It is a self-report questionnaire that is widely used to assess several dimensions of sleep with a total score of 0-21. Higher score means a worse outcome

Measure: The Pittsburgh Sleep Quality Index (PSQI) of exposed group

Time: immediately after the frontline workers isolated for two weeks

Description: It is a self-report questionnaire that is widely used to assess several dimensions of sleep with a total score of 0-21. Higher score means a worse outcome

Measure: The Pittsburgh Sleep Quality Index (PSQI) of exposed group

Time: immediately after the frontline workers going back to normal work for one month

Description: It is a self-report questionnaire that is widely used to assess several dimensions of sleep with a total score of 0-21. Higher score means a worse outcome

Measure: The Pittsburgh Sleep Quality Index (PSQI) of non-exposed group

Time: During the procedure of collecting faecal samples from non-exposed group

Description: It is a self-report instrument widely used to measure clinical psychiatric symptoms and mental health status, with a total score of 0-360. Higher means a worse outcome.

Measure: The Symptom Check List 90 (SCL-90) of exposed group

Time: immediately after the frontline workers come back to Xi'an

Description: It is a self-report instrument widely used to measure clinical psychiatric symptoms and mental health status, with a total score of 0-360. Higher means a worse outcome.

Measure: The Symptom Check List 90 (SCL-90) of exposed group

Time: immediately after the frontline workers isolated for two weeks

Description: It is a self-report instrument widely used to measure clinical psychiatric symptoms and mental health status, with a total score of 0-360. Higher means a worse outcome.

Measure: The Symptom Check List 90 (SCL-90) of exposed group

Time: immediately after the frontline workers going back to normal work for one month

Description: It is a self-report instrument widely used to measure clinical psychiatric symptoms and mental health status, with a total score of 0-360. Higher means a worse outcome.

Measure: The Symptom Check List 90 (SCL-90) of non-exposed group

Time: During the procedure of collecting faecal samples from non-exposed group

No related HPO nodes (Using clinical trials)