Correlated Drug Terms (2)

---

	Name (Synonyms)	Correlation
drug2519	Tigerase® and best available care Wiki	1.00
drug2938	other Wiki	0.71

Correlated MeSH Terms (1)

---

	Name (Synonyms)	Correlation
D018352	Coronavirus Infections NIH	0.04

Correlated HPO Terms (0)

---

	Name (Synonyms)	Correlation

Primary Outcomes

Measure: The proportion of patients with mechanical ventilation

Time: Day 8

---

Measure: Category change on WHO Ordinal Scale for Clinical Improvement

Time: Day 8

---

Secondary Outcomes

Measure: The proportion of patients with mechanical ventilation

Time: Day 28

---

Measure: Category change on WHO Ordinal Scale for Clinical Improvement

Time: Day 28

---

Measure: Proportion of patients surviving 28 days after inclusion in the study

Time: Day 28

---

Measure: Number of days of oxygen therapy during the treatment period

Time: Day 8

---

Measure: Change in C-reactive protein level

Time: Days 3, 5, 8

---

Description: PaO2 / FiO2, FiO2 = fraction of oxygen in inhaled air,% PaO2 = partial pressure of oxygen in arterial blood, mm Hg

Measure: Change in oxygenation index

Time: Days 3, 5, 8

---

Description: SpO2 / FiO2, FiO2 = fraction of oxygen in inhaled air,% SpO2 = hemoglobin oxygen saturation, %

Measure: Change in SpO2/FiO2 index

Time: Days 1, 2, 3, 4, 5, 6, 7, 8

---

Measure: Change in ferritin level

Time: Days 3, 5, 8

---

Measure: Change in D-dimer level

Time: Days 3, 5, 8

---

Measure: Change in neutrophil-leucocyte ratio

Time: Days 3, 5, 8

---

Measure: Change in leucocyte-C-reactive protein ratio

Time: Days 3, 5, 8

---

Measure: Change in the level of relative (%) number of lymphocytes of the general blood test

Time: Days 3, 5, 8

---