CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


CannabidiolWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (4)


Name (Synonyms) Correlation
drug232 Asthma reliever therapies Wiki 1.00
drug796 Dupilumab (SAR231893/REGN668) Wiki 1.00
drug231 Asthma controller therapies (incl. prednisone/prednisolone) Wiki 1.00
drug1738 PLACEBO Wiki 0.71

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D001249 Asthma NIH 0.50

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0002099 Asthma HPO 0.50

There is one clinical trial.

Clinical Trials


1 Cannabidiol (CBD) in Patients With Mild to Moderate Symptoms of Coronavirus 2019: A Randomized, Double-blind, Placebo-controlled Clinical Trial

The aim of this work is to conduct a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of cannabidiol (CBD - 300 mg a day) in patients infected with SARS-CoV-2. The specific objectives are to assess whether, in patients with mild and moderate forms of SARS-CoV-2, daily use of CBD 300 mg for fourteen days is capable of: i) decrease viral load; ii) modify inflammatory parameters, such as cytokines, measured from serum; iii) reduce clinical and emotional symptoms through daily clinical evaluation; iv) improve sleep; v) reduce hospitalization and worsen the severity of the disease; v) Monitor the possible adverse effects of CBD use in these patients.

NCT04467918 SARS-CoV2 Drug: Cannabidiol Other: PLACEBO

Primary Outcomes

Description: Mean reduction in viral load (reduction of ≥1 log10) over time during the study period

Measure: Reduction in viral load

Time: Up to 28 days

Secondary Outcomes

Description: Clinical CoVid19 symptoms improvement

Measure: Number of participants with negative Clinical CoVid19 symptoms as assessed by CTCAE v5.0

Time: Up to 28 days

Description: Immune reaction

Measure: Change in proinflammatory cytokine concentration

Time: Up to 28 days

Description: A qualitative CT analysis of parenchymal lung damage induced by COVID-19

Measure: Describe the parenchymal lung damage induced by COVID-19 through a qualitative analysis with chest CT

Time: 14 days

Description: Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]

Measure: Number of participants with treatment-related adverse events as assessed by CTCAE v5.0

Time: Up to 28 days

Description: Time to clinical improvement

Measure: Time to clinical improvement with CTCAE v5.0 CoVid19 symptoms to 0

Time: Up to 28 days

Description: CoVid severity worsening

Measure: Number of participants that need hospitalisation

Time: Up to 28 days

Description: Mortality

Measure: 28-day mortality

Time: Up to 28 days

Description: Time to negative saliva

Measure: Time to negative saliva 2019-n-CoV RT-PCR

Time: Up to 28 days


No related HPO nodes (Using clinical trials)