Correlated Drug Terms (1)

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	Name (Synonyms)	Correlation
drug833	Electrocardiogram, telemetry, echocardiogram, laboratory values Wiki	1.00

Correlated MeSH Terms (1)

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	Name (Synonyms)	Correlation
D002318	Cardiovascular Diseases NIH	0.21

Correlated HPO Terms (1)

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	Name (Synonyms)	Correlation
HP:0001626	Abnormality of the cardiovascular system HPO	0.21

Primary Outcomes

Measure: ICU mortality

Time: From the date of start of CytoSorb use until the date of ICU discharge or date of death, whichever comes first, assessed up to 1 year

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Secondary Outcomes

Measure: Duration of ECMO after start of CytoSorb

Time: From the date of start of CytoSorb use until the date of cessation of ECMO or date of death, which ever comes first, assessed up to 1 year

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Measure: Duration of mechanical ventilatory support after start of CytoSorb

Time: From the date of start of CytoSorb use until the date of cessation of mechanical ventilatory support or date of death, which ever comes first, assessed up to 1 year

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Measure: Duration of pharmacologic hemodynamic support after start of CytoSorb

Time: From the date of start of CytoSorb use until the date of cessation of pharmacologic hemodynamic support or date of death, which ever comes first, assessed up to 1 year

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Measure: Change in serum concentrations of inflammatory biomarkers after start of CytoSorb

Time: From the day before start of CytoSorb use until the day after cessation of CytoSorb use

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