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Colorectal resectionWiki

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drug1955 Pulse oximetry Wiki 1.00
drug500 CT-scan Wiki 1.00
drug815 EP Wiki 1.00
drug808 EEG Wiki 1.00
drug388 Blood tests Wiki 0.71

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D001927 Brain Diseases NIH 0.58

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HP:0001298 Encephalopathy HPO 0.58

There is one clinical trial.

Clinical Trials


1 Enhanced Recovery Pathways, Patient-reported Outcomes and Return to Intended Oncological Therapy After Colorectal Surgery: the Italian ColoRectal Anastomotic Leakage Study Group (iCral 3).

Prospective multicenter observational no-profit study evaluating the impact of ERAS program items adherence rates on patient-reported outcomes (PRO) and return to intendend oncologic therapy (RIOT) after colorectal resection. Prospective enrollment from November 2020 to October 2021 in 60 Italian surgical centers. All patients undergoing elective colorectal surgery with anastomosis will be included in a prospective database after written informed consent. A total of 3,000 patients is expected based on a mean of 50 cases per center.

NCT04397627 Colorectal Surgery Enhanced Recovery After Surgery Patient Reported Outcomes Procedure: Colorectal resection

Primary Outcomes

Description: Quality of life questionnaire based on five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. Scores ranging from 5 (worst) to 125 (best)

Measure: Change in patient-reported outcome measure #1; Health Questionnaire; Euro-QoL Group EQ-5D-5L™;

Time: Before the operation, postoperative day 5, 4 to 6 weeks after the operation

Description: Specific quality of life questionnaire for patients submitted to GI surgery: based on 24 questions with scores ranging from 0 (best) to 10 (worst); total score from 0 (best) to 240 (worst)

Measure: Change in patient-reported outcome measure #2; Health Questionnaire: MD Anderson Symptom Inventory for gastrointestinal surgery patients (MDASI-GI)

Time: Before the operation, postoperative day 5, 4 to 6 weeks after the operation

Description: Specific quality of life questionnaire for patients with colorectal cancer. Scores ranging form 0 (worst) to 144 (best).

Measure: Change in patient-reported outcome measure #3; Health Questionnaire Functional Assessment of Cancer Therapy - Colorectal® (FACT-C)

Time: Before the operation, postoperative day 5, 4 to 6 weeks after the operation

Description: Number of patients eligible for adjuvant therapy after surgery for colorectal cancer that receive appropriate treatment starting within 8 weeks after the operation

Measure: Return to intended oncologic therapy (RIOT)

Time: 8 weeks after the operation

Secondary Outcomes

Description: number of anastomotic leakage

Measure: Anastomotic leakage rate

Time: within 8 weeks from operation

Description: number of any perioperative adverse event graded according to Clavien-Dindo

Measure: Overall morbidity rate

Time: within 8 weeks from operation

Description: number of Clavien-Dindo grade >II perioperative adverse events

Measure: Major morbidity rate

Time: within 8 weeks from operation

Description: Total number of days spent in the hospital (including any readmission)

Measure: Length of hospital stay (LOS)

Time: within 8 weeks from operation


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