CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Diagnosis of SARS-Cov2 by RT-PCR and : IgG, Ig M serologies in the amniotoc fluid, the blood cord and the placentaWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug1344 Lifestyle intervention Wiki 1.00

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D050177 Overweight NIH 0.45
D063766 Pediatric Obesity NIH 0.45
D002908 Chronic Disease NIH 0.32

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Maternal-Foetal Transmission of COVID-19

One case of maternal-fetal transmission of SARS Cov-2 was published (1). Ig M and Ig G were found at two hours after birth of a new born from a mother COVID-19. Another study on few newborns COVID-19 reported that the SARS-Cov-2 was not transmitted in utero but only after birth. Although there are few data on COVID-19 during pregnancy, according to our national data collections, it appears to be responsible for miscarriages and fetal deaths. There are also intrauterine growth restrictions and an increase of the rate of cesarean sections for maternal indications. Therefore, it is essential to know if there is a maternal viremia which infects the fetus because the consequences in terms of management would be completely different. In fact, the potential intrauterine infection will lead to antenatal monitoring of these patients with an antenatal diagnosis and may be a treatment. Therefore, it seems essential to explore the mode of transmission to the newborn since many newborns have COVID-19 infection The investigators will propose to all pregnant women SARS- Cov-2 positive to perform PCR SARS-Cov-2 tests and /or serology's (IgM and Ig G) on the amniotic fluid, the blood cord and the placenta.

NCT04395924 Maternal Fetal Infection Transmission COVID-19 SARS-CoV 2 Diagnostic Test: Diagnosis of SARS-Cov2 by RT-PCR and : IgG, Ig M serologies in the amniotoc fluid, the blood cord and the placenta

Primary Outcomes

Description: COVID-19 by positive PCR in cord blood and / or positive serologies

Measure: COVID-19 by positive PCR in cord blood and / or positive serologies

Time: Day 0

Secondary Outcomes

Description: COVID-19 by positive PCR in amniotic fluid and placenta

Measure: COVID-19 by positive PCR in amniotic fluid and placenta

Time: Day 0

Description: Newborn baby infected with COVID-19 on gastric tubing, rectal sample, nasopharyngeal samples by COVID-19 PCR and blood samples by serology

Measure: New born infected by COVID-19

Time: Day 0


No related HPO nodes (Using clinical trials)