CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Double-Trunk MaskWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug2317 Standard interface Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D000860 Hypoxia NIH 0.23

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0012418 Hypoxemia HPO 0.23

There is one clinical trial.

Clinical Trials


1 Impact of the Double-Trunk Mask on Oxygenation Titration in Patients With COVID-19

This study will investigate the impact of the Double-Trunk Mask (DTM) on the reduction of oxygen titration in patients with severe hypoxemia.

NCT04346420 COVID Hypoxemia Other: Standard interface Device: Double-Trunk Mask
MeSH:Hypoxia
HPO:Hypoxemia

Primary Outcomes

Description: The O2 output will be adjusted to maintain a SpO2 of 94% using both systems for administering O2. The O2 flow will be read from the position of the ball in flow meters.

Measure: Change in O2 output

Time: At baseline and 30 minutes after wearing both systems

Secondary Outcomes

Description: A Likert scale from 0 to 5 will be used to measure the subjective comfort of the patient while wearing the standard interface for administering O2 and/or the DTM

Measure: Comfort with the interfaces

Time: 30 minutes after wearing both systems

Description: Oxygen tension (PaO2) in mmHg will be analyzed from a sample taken from the arterial system

Measure: Changes in PaO2

Time: At baseline and 30 minutes after wearing DTM

Description: Carbon dioxide tension (PaCO2) in mmHg will be analyzed from a sample taken from the arterial system.

Measure: Changes in PaCO2

Time: At baseline and 30 minutes after wearing DTM

Description: Potential of Hydrogen (pH) will be analyzed from a sample taken from the arterial system.

Measure: Changes in pH

Time: At baseline and 30 minutes after wearing DTM

Description: Respiratory rate is measured during one minute by visual inspection.

Measure: Changes in respiratory rate

Time: At baseline and 30 minutes after wearing both systems


Related HPO nodes (Using clinical trials)