CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Blink and Masseter Inhibitory ReflexWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug619 Compassion focused intervention Wiki 1.00
drug245 Auditory Evoked Potentials (AEP) Wiki 1.00
drug731 Deep Breathing training Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D001930 Brain Injuries, NIH 0.38

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Exploring Brain Damages After COVID-19 Infection

Although direct evidence is currently lacking, the high identity between SARS-CoV-1 and SARS-CoV-2 suggests, that the latter viral strain could also infect the Central Nervous System (CNS). Indeed, some cases of SARS-COV2 encephalitis begin to be described and CNS damages are increasingly highlighted in the literature, but still not objectified by imaging and do not allow to explain the entire clinical patterns. We hypothesise that these CNS damages are not always objectified by Magnetic Resonance Imaging (MRI) but could be indirectly observed by a physiological dysfunction of neural conduction in the brainstem. We will explore brainstem disruption through an electrophysiological approach.

NCT04405986 SARS-CoV 2 Procedure: Auditory Evoked Potentials (AEP) Procedure: Blink and Masseter Inhibitory Reflex
MeSH:Brain Injuries

Primary Outcomes

Description: Latencies of electrophysiological responses with Auditory Evoked Potentials

Measure: Latency of electrophysiological response

Time: Inclusion (T0)

Description: Delay of Muscle contraction (Blink reflex)

Measure: Delay of Muscle contraction

Time: Inclusion (T0)

Description: Delay of silent period while the patient is asked to tighten the jaws (Masseter Inhibitory Reflex)

Measure: Delay of silent period

Time: Inclusion (T0)

Description: Duration of silent period while the patient is asked to tighten the jaws (Masseter Inhibitory Reflex)

Measure: Duration of silent period

Time: Inclusion (T0)

Description: Inhibition rate while the patient is asked to tighten the jaws (Masseter Inhibitory Reflex)

Measure: Inhibition rate

Time: Inclusion (T0)


No related HPO nodes (Using clinical trials)