Name (Synonyms) | Correlation | |
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D009748 | Nutrition Disorders NIH | 1.00 |
D016638 | Critical Illness NIH | 0.14 |
Name (Synonyms) | Correlation |
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There is one clinical trial.
The investigator will investigate the effect of supplemental enteral protein (1.2 g/kg/day) added to standard formula to achieve high amount of enteral protein (range 2-2.4 g/kg/day) given from ICU day 5 until ICU discharge up to ICU day 90 as compared to no supplemental enteral protein to achieve moderate amount enteral protein (0.8-1.2 g/kg/day), given in conjunction with similar amounts of stepwise caloric administration in the two groups on all-cause 90-day mortality.
Description: Mortality 90 days post randomization
Measure: 90 day-all cause mortality Time: 90 daysDescription: use of vasopressor/inotropic support, invasive mechanical ventilation and/or renal replacement therapy
Measure: Days alive at day 90 without life support Time: 90 daysDescription: 90 day survival after randomization
Measure: Days alive and out of hospital at day 90 Time: 90 daysDescription: Any symptoms of bacteremia
Measure: Bacteremia until 2 days of ICU stay Time: until 2 days post ICU.Description: anytime during ICU stay
Measure: New or progression of Skin Pressure Ulcers Time: ICU stayDescription: SARC-F screen for sarcopenia and EuroQoL
Measure: Functional assessment at day 90 Time: Day 90Description: New episode of stage 2 or higher AKI by KDIGO criteria; 2. Pneumonia defined as episodes of newly confirmed pneumonia according to the modified CDC criteria; 3. Grade IV Acute Gastrointestinal injury (AGI)
Measure: Safety outcomes during ICU stay Time: ICU stayDescription: Feeding tolerance; Diarrhoea; Refeeding syndrome
Measure: Minor safety outcomes during ICU stay Time: ICU stay