CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

DexmethylphenidateWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)

Name (Synonyms) Correlation
drug848 Endoscopic management according to standard of care Wiki 1.00

Correlated MeSH Terms (6)

Name (Synonyms) Correlation
D007565 Jaundice, NIH 1.00
D002761 Cholangitis NIH 1.00
D018281 Cholangiocarcinoma NIH 1.00
D008105 Liver Cirrhosis, Biliary NIH 1.00
D041781 Jaundice, Obstructive NIH 1.00
D010190 Pancreatic Neoplasms NIH 0.58

Correlated HPO Terms (5)

Name (Synonyms) Correlation
HP:0030153 Cholangiocarcinoma HPO 1.00
HP:0002613 Biliary cirrhosis HPO 1.00
HP:0000952 Jaundice HPO 1.00
HP:0030151 Cholangitis HPO 1.00
HP:0002894 Neoplasm of the pancreas HPO 0.58

There is one clinical trial.

Clinical Trials

1 An Open-label, Randomized, Single-dose, Two-period, Two-treatment (Fed vs Fasted), Two-sequence, Crossover Study in Healthy Adult Subjects to Assess the Effect of Food on the Absorption and Bioavailability of CTx-1301 (Dexmethylphenidate)

The primary purpose of this study is to assess the effect of food on the rate and extent of absorption and the overall bioavailability of a single dose of CTx-1301 50 mg trimodal tablets in healthy adult volunteers.

NCT04449250 Healthy Volunteers in Fed and Fasted State Drug: Dexmethylphenidate

Primary Outcomes

Measure: Pharmacokinetic parameter (Cmax)

Time: Hour 0 to hour 28

Measure: Pharmacokinetic parameter (AUC0-inf)

Time: Hour 0 to hour 28

Measure: Pharmacokinetic parameter (AUC0-last)

Time: Hour 0 to hour 28

Secondary Outcomes

Measure: Pharmacokinetic parameter (AUC0-3)

Time: Hour 0 to hour 3

Measure: Pharmacokinetic parameter (AUC3-6)

Time: Hour 3 to hour 6

Measure: Pharmacokinetic parameter (AUC6-9)

Time: Hour 6 to hour 9

Measure: Pharmacokinetic parameter (AUC9-12)

Time: Hour 9 to hour 12

Measure: Pharmacokinetic parameter (AUC12-16)

Time: Hour 12 -16

Measure: Pharmacokinetic parameter K

Time: Hour 0 to hour 28

Measure: Pharmacokinetic parameter T1/2

Time: Hour 0 to hour 28

Measure: Pharmacokinetic parameter Tmax

Time: Hour 0 to hour 28

Measure: Pharmacokinetic parameter Tlag

Time: Hour 0 to hour 28

No related HPO nodes (Using clinical trials)