CovidResearchTrials by Shray Alag


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Hemodynamics changes at different PEEPWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (5)


Name (Synonyms) Correlation
drug992 Gas exchanges at different PEEP Wiki 1.00
drug2875 lung mechanics at different PEEP Wiki 1.00
drug186 Anti-SARS-CoV2 serological controls and serum neutralization Wiki 1.00
drug185 Anti-SARS-CoV2 Serology Wiki 0.71
drug1978 Questionnaire Wiki 0.21

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D055371 Acute Lung Injury NIH 0.10
D012127 Respiratory Distress Syndrome, Newborn NIH 0.10
D012128 Respiratory Distress Syndrome, Adult NIH 0.09

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Avoiding High PEEP in COVID-19 Induced ARDS: a Multi-center Study

This was a multi-center prospective study. All consecutive severe cases of COVID-19 whose PO2/FiO2<300mmHg with invasive ventilation admitted to 5 fixed-point receive COVID-19 patients hospitals in Wuhan from 5 March to 15 March 2020 were included. Epidemiological, clinical data, lung mechanics, artery blood gas test and hemodynamics at three methods to titrate PEEP, optimizing oxygenation, optimizing compliance, ARDSnet. The study was approved by the Ethics Committee of Zhongda Hsopital, Southeast University.

NCT04359251 COVID-19 Mechanical Ventilation Pressure High Acute Respiratory Distress Syndrome Other: Gas exchanges at different PEEP Other: lung mechanics at different PEEP Other: Hemodynamics changes at different PEEP
MeSH:Respiratory Distress Syndrome, Newborn Respiratory Distress Syndrome, Adult Acute Lung Injury

Primary Outcomes

Description: the respiratory system compliance was compared among three groups

Measure: Respiratory system compliance improvement

Time: 20 minutes

Secondary Outcomes

Description: P/Fwere compared among three groups

Measure: Gas echanges improvement

Time: 20 minutes

Other Outcomes

Description: MAP were compared among three groups

Measure: hemodynamics improvement

Time: 20 minutes


No related HPO nodes (Using clinical trials)