CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

Biospecimen collectionWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


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D000755 Anemia, Sickle Cell NIH 1.00

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There is one clinical trial.

Clinical Trials

1 Risks of COVID19 in the Pregnant Population

It is unclear how COVID19 can be passed from mother to infant. The study investigators aim to collect maternal and neonatal samples from COVID19-infected pregnant women and compare them to pregnant women who have clinical indications for COVID 19 testing at the time of hospital admission but end up being COVID19 negative. Pregnant women who are either COVID19 positive or COVID19 negative with respiratory symptoms will be enrolled and followed during this study.

NCT04379284 COVID19 Other: Biospecimen collection

Primary Outcomes

Description: Standardized testing of maternal, placental, and neonatal specimens will be used to determine presence of current infection with SARS-CoV2. Clinical RT-PCR assays will be used to determine the presence of viral RNA in all specimens.

Measure: Determine the prevalence of maternal fetal transmission of COVID19

Time: 12 months

Secondary Outcomes

Description: Clinical data from prenatal, intrapartum, and postpartum care will be abstracted from maternal records and correlated with neonatal outcomes. Any complications will be characterized, with comparison to the non-COVID19 control group of patients. Statistical analysis will reveal characteristics and clinical outcomes that may be linked to COVID19 infection in pregnancy.

Measure: Describe the outcomes of COVID19 positive pregnancies

Time: 12 months

Description: In addition to maternal and fetal infection, disease states related to placental dysfunction may be related to COVID19 infection in pregnancy. We will examine placenta and markers of placental function to assess for discernable consequences of maternal infection.

Measure: Understand the placental impact of COVID19 in pregnancy at various gestational ages

Time: 12 months

No related HPO nodes (Using clinical trials)