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Cooking TrainingWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (4)


Name (Synonyms) Correlation
drug2437 Table Setting Training Wiki 1.00
drug844 Emtricitabine/Tenofovir Alafenamide 200 MG-25 MG Oral Tablet Wiki 1.00
drug1526 Multi-tasking Training Wiki 1.00
drug1822 Placebo Wiki 0.06

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D060825 Cognitive Dysfunction NIH 0.35

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0001268 Mental deterioration HPO 0.35

There is one clinical trial.

Clinical Trials


1 Cognitive Training in a Multi-task Daily Life Task: a Feasibility Study in Healthy Older Adults

This study evaluated the feasibility of a web-based computerized cognitive training protocol to healthy older adults. The training protocol will occur in two phases. In the first phase, participants will be randomly allocated in one type of training, and in the second phase all participants will receive the same training.

NCT04195230 Age-related Cognitive Decline Behavioral: Table Setting Training Behavioral: Cooking Training Behavioral: Multi-tasking Training
MeSH:Cognitive Dysfunction
HPO:Cognitive impairment Mental deterioration

Primary Outcomes

Description: Change in cooking time (milliseconds) in each food type. In the computerized task, participants are asked to cook different food types. Scores reflect the average absolute values of the difference between the required and actual cooking time of each item. Lowers scores (closest to zero) represent a better outcome.

Measure: Change in Cooking Time Discrepancy Scores

Time: During intervention: baseline, two weeks, and one month

Description: Change in cooking time (milliseconds) between food items. In the computerized task, participants are asked to cook different food types. Scores reflect is the difference between the first and last food item stopped cooking. Lowers scores (closest to zero) represent a better outcome.

Measure: Change in Range of Stop Times Score

Time: During intervention: baseline, two weeks, and one month

Description: Change in the total number of tables set. In the computerized task, participants are asked to set tables for four guests, when finished, one point is given. Higher scores represent a better outcome.

Measure: Change in the Number of Tables Set Score

Time: During intervention: baseline, two weeks, and one month

Secondary Outcomes

Description: The participants are asked to identify targets and ignore distracting visual information under different conditions. Scores are automatically generated by the software based on the accuracy and reaction time of performance. Higher scores reflect better cognitive ability.

Measure: Transfer to Speed Processing Task (Change)

Time: Baseline, two weeks (during the intervention), within one week after the intervention

Description: Participants are presented with a computer screen of 9 boxes. The boxes light up in a pre-fixed sequence and participants are asked to click on the boxes in the same order they were lit. The sequence length starts at level = 2 boxes and can increase to up to level 9. One point is giving for each correct response. Higher values represent better performance (min 0; max of 16 points).

Measure: Transfer to Visuospatial Working Memory Task (Change)

Time: Baseline, two weeks (during the intervention), within one week after the intervention

Description: Participants are asked to read words and identify letter under different conditions. Scores are based on performance time (seconds) and number of errors.

Measure: Transfer to Inhibitory Control Task (Change)

Time: Baseline, two weeks (during the intervention), within one week after the intervention

Description: Participants listen to series of letters and digits, which they need to organize under specific conditions. One point is giving for each correct response (mix 0; max 30 points).

Measure: Transfer to Verbal Working Memory Task (Change)

Time: Baseline, two weeks (during the intervention), within one week after the intervention

Description: It consists in a test that target three attentional networks involving identifying targets. Lower score represent faster performance.

Measure: Transfer to Complex Attention Task (Change)

Time: Baseline, two weeks (during the intervention), within one week after the intervention

Description: It consist in letters and numbers operations. Accuracy on the alphabetic portion of the Alpha-span task.

Measure: Transfer to Complex Working Memory Task: the Alpha-span task (Change)

Time: Baseline, two weeks (during the intervention), within one week after the intervention

Description: Average z-score computed with outcomes 4 to 9.

Measure: Transfer to Executive Control Composite Score (Change)

Time: Baseline, two weeks (during the intervention), within one week after the intervention

Description: Questionnaire listing cognitive failures in everyday life (self-report measure). Higher scores reflect more cognitive failures or difficulties.

Measure: Transfer to self-report cognitive failure questionnaire (Change)

Time: Baseline, two weeks (during the intervention), within one week after the intervention


Related HPO nodes (Using clinical trials)


HP:0100543: Cognitive impairment
Genes 871
PDGFRB FGFR3 CAMTA1 GLB1 CHD2 EDN3 SYNJ1 CLN6 FMR1 TOMM40 GBA SLC13A5 REEP2 COX1 DAOA TSFM XPA EPCAM SPTBN2 PLAU MEFV ATP1A3 PINK1 TBP COASY MAPT UCHL1 CHD2 TSC1 TYMP SLC13A5 SCN8A SCN8A RBM12 SNCA PEX1 GLA CHMP2B CCR1 WWOX TRNL1 ND4 PDGFB MLH3 MSH2 NUP133 APOL2 NR4A2 KCNQ3 VPS13A CFH GIGYF2 WDR45 DNMT1 AKT1 SDHB TRNL1 TTPA GBA PDGFRB XRCC4 CCDC78 PEX10 NUP107 MAPT CACNA1B CHRNG MAG KCNT1 HGSNAT C4A ERCC2 ALDH18A1 VPS13C SCN8A GABRG2 ABCA12 SQSTM1 PLP1 PEX12 CUX2 FA2H PNKP ALDH18A1 ARSA ROGDI MAPT WFS1 PTPN22 MFSD8 PSEN2 JAM2 DGUOK LZTFL1 DCAF17 SUFU SCN1B NHLRC1 EEF1A2 KCNB1 UBQLN2 GNAS SDHD HTRA1 NF2 FAS ZFYVE26 HNRNPA2B1 NPC1 CTC1 MYH3 SLC2A3 TARDBP DNMT1 SEC61A1 PSAP PLA2G6 TTC19 CLN5 POLG SMO HNF1A SNCAIP LRRK2 PRKCG TRNW ATP7B CLTC PRDM8 SUMF1 BAP1 B3GALNT2 TSC2 IRF6 SPG7 COMT CYP2U1 GALC CHMP2B STAT4 ALG9 DNMT1 IL23R PLAA ERAP1 UBA5 ATP13A2 DMPK NOS3 UQCRC2 RBM28 NPHP1 DNAJC5 TGM1 DOLK NKX6-2 MSH6 WFS1 PMS1 CFHR1 ATN1 POLG DCC OPA3 PRKAR1A TRNF SEC23B PARS2 RBM28 IRAK1 CHRM3 RAB39B DNAJC6 GSN ND6 AKT1 RRM2B MAPT GALC HLA-B SDHD POLG TTC8 LMNB1 COL18A1 DDB2 APP ATXN7 PLK4 ERCC4 PRKRA SLC2A1 PSEN1 SCN9A PRDX1 ERCC6 EIF2B1 PEX13 SNCA MEOX1 FA2H RPS20 PTEN NOTCH3 FGF12 COL5A2 NDUFAF3 TREM2 BBS10 ATR TRAIP SLC7A7 SCN2A TIMM8A FTL GDAP2 PAH MAPT EIF4G1 AP5Z1 KCNA2 NBN ERCC4 DNM1L ND6 ADA2 KRT6A GNAS TRNL1 MTO1 LIPN SCN1B ALG2 FGF14 CST3 CTSH ND1 SDR9C7 SDHD ITPR1 C9ORF72 HNRNPA2B1 DNM1 PIK3CA DRD3 EIF2B3 CHCHD10 TREX1 SCN3A GPC4 ATXN10 CEP152 NAGS NDUFB8 PSEN1 GBA2 CHMP2B PEX16 PMS2 POLG UBTF TRNF MAOA ERCC5 SYNJ1 ATXN8OS SNCA CYP4F22 FUS PLA2G6 SLC18A2 SNCA TBCK ARSA PIK3CA PPP2R2B PDE10A KRT81 ND1 SPG11 GALC SCN1A MTHFR IFT140 GJB6 JPH3 GRID2 PODXL SPAST ABCD1 SLC2A1 DISC2 C9ORF72 PEX19 FKTN GABRA1 BBS12 COASY BDNF LRRK2 GBA CYTB NAGLU PHOX2B PPT1 POMGNT1 RNF216 KCNJ11 TGFBR2 MARS2 COL4A1 HCRT PLEKHG4 APP MMACHC MBTPS2 TMEM106B ABCA7 SDHAF1 AFG3L2 IKBKG POMT1 POLG MFN2 VPS37A SEMA4A HEXA ATP6V0A2 TWNK POLG2 WDR45 DGUOK HTRA2 TMEM240 TRNS2 CYFIP2 EIF2B5 TBC1D24 PRDM8 VPS35 UBA1 CYP7B1 ATXN3 HTT SYNJ1 TRAF7 GMPPB CACNA1G GRN PIK3CA EPRS1 PNPLA6 TYROBP TBK1 TREM2 BAP1 CRLF1 PINK1 PEX11B BSCL2 GRN MAPT VCP VAMP1 BMPR1A CENPJ ERCC3 TARDBP SLC6A1 SMC3 TBK1 ERF PRICKLE1 MEN1 APOE ROGDI POLG GNPTAB PSEN1 ATRIP BBS5 NDUFA6 APP ATM PRKAR1B STAT4 PRNP B3GALNT2 ATP6 SQSTM1 SMC1A CENPJ ADAMTSL4 ACTB GBA ACSF3 SMARCB1 SPART SPG11 CERS1 SQSTM1 STXBP1 TUBB4A APP PRNP C9ORF72 ITGA7 CNTNAP2 MLH1 ATXN2 DCTN1 ALOX12B ABCA7 PRNP SLC20A2 ARL6IP6 RBBP8 PPP2R2B VCP TMEM106B CFAP43 AFG3L2 MTFMT APP SCN1A ATXN7 ATP6V1E1 KCNQ3 PDE11A SUMF1 PSAP GABRA5 C12ORF65 ATXN1 SMARCE1 C12ORF65 FAS MTOR POMT2 GM2A MCOLN1 KCND3 GBE1 ATP1A2 LAGE3 SLC30A9 PRNP CFHR3 DSTYK HEPACAM DNAJC13 HTT POMK TNFSF4 EIF2B4 PSAP HLA-DRB1 TREM2 OCRL NOTCH3 IL12A-AS1 CNKSR2 CTSK SCN1A AARS2 SLC1A2 VPS13C GABRG2 RRM2B UGT1A1 PSEN1 ADGRV1 SMC1A ERCC3 TRNC KMT2B MAPT GDNF EPM2A WDR4 C19ORF12 SYNJ1 CP ADD3 TRNK TRNK TRAK1 XPC HLA-DQB1 KLRC4 ERCC8 LRRK2 PEX6 HSD17B10 PRNP TRNQ COQ2 ATXN3 GABRA2 SCO2 NDUFS2 KMT2A PSEN2 GNAS SPG11 FGD1 TLR3 MYD88 TRPM7 GBE1 SNCA GCH1 GJC2 UBAP1 COX3 GRN FTL FMR1 TUBA4A MAPT ZNF365 ROBO3 KIF5A LAMA2 ATXN1 APTX MAPT DMD GBA LAMP2 SDHC SLC25A4 TRNS1 CCM2 TBP GALC KCTD7 CISD2 TRNQ APOE GBA SLC18A2 SPP1 PRNP TBP HFE PRRT2 CLN3 QDPR STUB1 TRNS1 CHCHD10 TWNK ARSA TRNH NAGS C9ORF72 CACNA1A MAPT DARS2 PEX14 CP PORCN RNR1 RNF216 IL12A AP5Z1 SDHAF1 MAPT C12ORF65 GABRG2 XPR1 SGPL1 KRT16 TSC1 METTL23 MYORG CEP120 GRN GCDH RNASEH1 ADA2 PDGFRB ATXN2 HTR2A NECAP1 SZT2 CLN6 KRT86 SLC25A15 AARS1 TRNS2 SPG7 OSGEP UCP2 PSAP ALG12 A2M EPM2A YWHAG CSTB COX1 CHMP2B ND5 NFIA TRNH JPH3 ITPR1 TIMM8A IDUA PCDH19 PTS KCNA2 GABRD TRNS2 SULT2B1 CYP2U1 PRNP FBXO7 NDP RMRP LTBP4 GRN TK2 GJB2 FBN1 ERCC2 FGF14 TUBB2B P2RY11 COX2 DHDDS RAB27A KCNQ2 CTNS DNAJC3 MECP2 ATP6 TMEM106B SNORD118 HCN1 PEX2 RTN4R SLC25A4 ASAH1 SCN2A SYNGAP1 BRAF OPA1 GBA ATP13A2 CTSD PNKP HNRNPA1 ABCA5 ATXN3 ADH1C SLC25A13 CHI3L1 PDGFB SIM1 ACTL6B GDF6 CSF1R CTNS TRNP SRCAP TRNQ SURF1 ATP6V1A CLCF1 NAGA MAPT GMPPB ATP1A3 RRM2B MATR3 PDCD10 DSG4 PANK2 KCNC1 HTT SCN9A PEX5 HSD17B4 NRAS RRM2B CTDP1 BSCL2 AUH MPO GDF3 ATXN3 HIBCH SERPINI1 CPLX1 SCN2A NTRK2 MYO1H PEX26 ITM2B COX3 PRNP CLN8 CSTB TTC37 NPC2 SQSTM1 TRNV NIPAL4 HTRA1 RNASEH1 CYP27A1 TWNK ABCC8 UBAC2 STARD7 AP2M1 POLG TPRKB ATP13A2 SPG21 PRKCG ATN1 GTPBP3 FKRP SYN2 PARK7 PCNT PDGFB NOTCH2NLC KCNQ2 TREM2 EIF2B2 ALOXE3 TRNK TSC2 AP3B2 TLR4 PANK2 APOL4 SOST KATNB1 STXBP1 VCP FAN1 NUS1 TREM2 CENPE PSEN1 TYROBP AASS PANK2 TWNK MATR3 ATP6V1A SNCA GNE TERT KLLN GRIN2D CSF1R TTR DNM1 ATG5 COX2 PANK2 TRNF SDHA XPA SORL1 ATXN2 GNAS SCARB2 GJC2 APP GM2A ATP13A2 TK2 KRT83 DARS2 IL10 FLNA SPR PSEN1 VCP ATP13A2 BRAF ITM2B IBA57 NHLRC1 HCN1 TINF2 CLN8 TBK1 LARGE1 VPS13A ARV1 RIN2 ASAH1 HNF4A APP COL5A1 HEXB CTSF LAMA1 TRNW VAMP1 SDCCAG8 WDR73 C19ORF12 BBIP1 MOG SPG21 SDHA PRKN TP53 KRT17 TP53RK KRAS TIMMDC1 SPTBN2 ND5 SPAST PPP3CA SNCB GABRB2 CUBN COL1A1 HLA-DQB1 STX1B SDHB MPDU1 C9ORF72 TREX1 DCTN1 SLC5A7 CLMP FA2H PSEN1 VCP TRNE PEX16 GABRB3 GBA2 USF3 TRNS1 TMEM240 STUB1 C9ORF72 ND5 GDF5 PEX3 POMT2 VCP PRNP CHMP2B GRID2 MAPT SCN1A MAPK10 KRIT1 KRT6B ECM1 PLA2G6 AIFM1 ALG13 PGM3 COL3A1 GLUD2 DNAJC6
Protein Mutations 0
SNP 0
HP:0001268: Mental deterioration
Genes 478
PDGFRB HEPACAM DNAJC13 GLB1 HTT CHD2 SYNJ1 CLN6 FMR1 PSAP TOMM40 GBA SLC13A5 COX1 DAOA XPA TREM2 NOTCH3 PLAU ATP1A3 CNKSR2 AARS2 PINK1 SLC1A2 VPS13C TBP MAPT UCHL1 CHD2 PSEN1 TYMP SLC13A5 TRNC MAPT SCN8A EPM2A C19ORF12 SYNJ1 SNCA CP CHMP2B WWOX TRNK TRNL1 ND4 PDGFB TRAK1 APOL2 NR4A2 ERCC8 VPS13A LRRK2 HSD17B10 GIGYF2 WDR45 PRNP TRNQ DNMT1 SDHB TTPA GABRA2 SCO2 NDUFS2 GBA KMT2A PSEN2 PDGFRB SPG11 TLR3 TRPM7 SNCA GCH1 MAPT CACNA1B UBAP1 COX3 GRN FTL FMR1 TUBA4A HGSNAT ERCC2 ALDH18A1 VPS13C MAPT SQSTM1 PLP1 CUX2 FA2H APTX MAPT GBA ALDH18A1 ARSA TBP ROGDI MAPT GALC KCTD7 WFS1 CISD2 TRNQ APOE GBA MFSD8 PRNP PSEN2 JAM2 TBP HFE DCAF17 CLN3 QDPR NHLRC1 EEF1A2 TRNS1 KCNB1 UBQLN2 GNAS CHCHD10 ARSA TRNH SDHD HTRA1 ZFYVE26 HNRNPA2B1 NPC1 CTC1 C9ORF72 SLC2A3 CACNA1A MAPT TARDBP DARS2 CP DNMT1 RNF216 PSAP PLA2G6 SDHAF1 MAPT GABRG2 CLN5 XPR1 SGPL1 MYORG HNF1A SNCAIP LRRK2 PRKCG GRN TRNW ATP7B CLTC PRDM8 SUMF1 ADA2 PDGFRB IRF6 COMT ATXN2 GALC CHMP2B HTR2A NECAP1 SZT2 CLN6 DNMT1 AARS1 UBA5 ATP13A2 TRNS2 DMPK UCP2 NOS3 PSAP RBM28 A2M EPM2A YWHAG CSTB DNAJC5 COX1 CHMP2B WFS1 ATN1 ND5 PRKAR1A PARS2 JPH3 RBM28 TIMM8A RAB39B IDUA ND6 RRM2B MAPT GALC PTS KCNA2 LMNB1 COL18A1 APP ATXN7 PRNP FBXO7 ERCC4 PSEN1 NDP GRN PRDX1 ERCC6 SNCA FA2H NOTCH3 COX2 FGF12 NDUFAF3 TREM2 DHDDS RAB27A TIMM8A FTL GDAP2 PAH CTNS MAPT MECP2 ATP6 TMEM106B SNORD118 EIF4G1 AP5Z1 KCNA2 NBN HCN1 DNM1L ND6 RTN4R ADA2 ASAH1 TRNL1 SYNGAP1 CST3 ND1 OPA1 C9ORF72 HNRNPA2B1 DNM1 GBA DRD3 CTSD CHCHD10 HNRNPA1 TREX1 SCN3A ATXN10 NDUFB8 ATXN3 PSEN1 ADH1C GBA2 CHMP2B CHI3L1 PDGFB ACTL6B POLG CSF1R UBTF TRNF SURF1 ATP6V1A SYNJ1 ATXN8OS SNCA MAPT FUS PLA2G6 RRM2B MATR3 SNCA PANK2 ARSA PPP2R2B KCNC1 HTT PDE10A ND1 NRAS SPG11 RRM2B GALC BSCL2 SCN1A MTHFR MPO HIBCH SERPINI1 CPLX1 JPH3 NTRK2 PODXL ITM2B COX3 SPAST ABCD1 DISC2 C9ORF72 PRNP CLN8 COASY CSTB NPC2 LRRK2 SQSTM1 GBA CYTB NAGLU TRNV PPT1 RNF216 KCNJ11 HTRA1 RNASEH1 COL4A1 CYP27A1 TWNK ABCC8 PLEKHG4 APP AP2M1 MMACHC MBTPS2 TMEM106B ATP13A2 SPG21 ATN1 MFN2 SYN2 HEXA ATP6V0A2 PARK7 WDR45 DGUOK HTRA2 NOTCH2NLC TRNS2 CYFIP2 TBC1D24 TREM2 PRDM8 VPS35 HTT SYNJ1 TRNK AP3B2 GRN APOL4 PNPLA6 STXBP1 VCP TYROBP NUS1 TREM2 PSEN1 TYROBP TBK1 TREM2 PANK2 PINK1 MATR3 ATP6V1A SNCA BSCL2 GRN GRIN2D CSF1R TTR DNM1 COX2 MAPT TRNF SDHA VCP SORL1 ATXN2 TARDBP SCARB2 SLC6A1 APP GM2A TBK1 PRICKLE1 ATP13A2 APOE ROGDI POLG TK2 PSEN1 NDUFA6 PSEN1 APP PRKAR1B VCP ATP13A2 PRNP ITM2B ATP6 NHLRC1 SQSTM1 TINF2 CLN8 TBK1 ARV1 SMC1A ASAH1 ACTB HNF4A GBA APP HEXB CTSF CERS1 SQSTM1 TRNW TUBB4A APP PRNP C9ORF72 C19ORF12 CNTNAP2 SPG21 PRKN TIMMDC1 ATXN2 DCTN1 ND5 ABCA7 PPP3CA SNCB GABRB2 CUBN PRNP HLA-DQB1 SLC20A2 C9ORF72 TREX1 DCTN1 PPP2R2B VCP TMEM106B FA2H CFAP43 PSEN1 VCP TRNE GABRB3 GBA2 APP SCN1A TRNS1 ATXN7 ATP6V1E1 PDE11A SUMF1 PSAP GABRA5 VCP CHMP2B MAPT MAPK10 PLA2G6 MCOLN1 GBE1 ATP1A2 PRNP GLUD2 DNAJC6
Protein Mutations 3
K56M V158M V66M