Name (Synonyms) | Correlation |
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There is one clinical trial.
The SARS-CoV-2 infection caused clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus and was associated with ICU admission and high mortality. There is no confirmed antivirus therapy for people infected SARS-CoV-2, most of them should receive supportive care to help relieve symptoms. For severe cases, treatment should include care to support vital organ functions. This clinical trial is to inspect the safety and efficiency of Mesenchymal Stem Cells (MSCs) therapy for pneumonia patients infected with SARS-CoV-2.
Description: Evaluation of Pneumonia Improvement
Measure: Size of lesion area by chest radiograph or CT Time: At Baseline , Day 3, Day 6, Day 10, Day 14, Day 21,Day 28Description: Number of participants with treatment-related adverse events as assessed by CTCAE v4.0
Measure: Side effects in the MSCs treatment group Time: At Baseline , Day 3, Day 6, Day 10, Day 14, Day 21, Day 28, Day 90 and Day 180Description: Evaluation of Pneumonia Improvement
Measure: Improvement of Clinical symptoms including duration of fever and respiratory Time: At Baseline , Day 3, Day 6, Day 10, Day 14, Day 21, Day 28Description: Marker for COVID-19
Measure: Time of nucleic acid turning negative Time: At Baseline , Day 3, Day 6, Day 10, Day 14, Day 21, Day 28, Day 90 and Day 180Description: Marker for efficacy of treatment
Measure: Rate of mortality within 28-days Time: Day 28Description: Marker of Immunological function
Measure: CD4+ and CD8+ T celll count Time: At Baseline , Day 3, Day 6, Day 10, Day 14, Day 21, Day 28, Day 90 and Day 180Description: Markers of organ function
Measure: Alanine aminotransferase Time: At Baseline , Day 3, Day 6, Day 10, Day 14, Day 21, Day 28, Day 90 and Day 180Description: Markers of Infection
Measure: C-reactive protein Time: At Baseline , Day 3, Day 6, Day 10, Day 14, Day 21, Day 28, Day 90 and Day 180Description: Markers of organ function
Measure: Creatine kinase Time: At Baseline , Day 3, Day 6, Day 10, Day 14, Day 21, Day 28, Day 90 and Day 180