Name (Synonyms) | Correlation | |
---|---|---|
drug1695 | Ontamalimab Wiki | 0.50 |
drug1822 | Placebo Wiki | 0.06 |
Name (Synonyms) | Correlation | |
---|---|---|
D014456 | Ulcer NIH | 0.41 |
D003092 | Colitis NIH | 0.41 |
D003093 | Colitis, Ulcerative NIH | 0.41 |
Name (Synonyms) | Correlation | |
---|---|---|
HP:0002583 | Colitis HPO | 0.41 |
HP:0100279 | Ulcerative colitis HPO | 0.41 |
There is one clinical trial.
The aim is to develop a wearable-based ICU (intensive care unit) prediction algorithm for inpatients contracted with SARS-CoV-2. Inpatients with suspicion of COVID-19 or with confirmed SARS-CoV-2 infection will be included. The participants will be equipped with a smartwatch, which gathers physiological data throughout hospitalisation.
Description: Accuracy of the WAVE-model will be assessed using physiological data recorded by the smartwatch (Garmin vivoactive 4) during hospitalization complemented by demographic and health-related patient-information and will be analysed using applied machine learning technology for ICU prediction.
Measure: Diagnostic accuracy of smartwatch data in predicting ICU requirement in COVID-19 contracted inpatients quantified as the area under the receiver operator characteristics curve (AUC ROC > 0.85). Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Accuracy of the model will be assessed using physiological data routinely recorded during hospitalization and will be analysed using applied machine learning technology for ICU prediction.
Measure: Diagnostic accuracy of routine physiological data in predicting ICU requirement in COVID-19 contracted in-patients quantified as the area under the receiver operator characteristics curve (AUC ROC > 0.85). Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Accuracy of the model will be assessed using data on comorbidities, medication treatment during hospitalization and physiological data and will be analysed using casual machine-learning approaches
Measure: Diagnostic accuracy of predicting hospital discharge without ICU admission in COVID-19 contracted in-patients quantified as area under the receiver operator characteristics curve Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Heart rate will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors.
Measure: Change of heart rate from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Heart rate variability will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of heart rate variability from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Skin temperature will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of skin temperature from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Blood oxygen saturation will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors
Measure: Change of blood oxygen saturation from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Respiration rate will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors
Measure: Change of respiration rate from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Physical activity will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of physical activity from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Stress level will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of stress level from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Sleep will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of sleep pattern from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Steps per day will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)
Measure: Change of steps per day from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Systolic blood pressure will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors
Measure: Change of systolic blood pressure from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Diastolic blood pressure will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors
Measure: Change of diastolic blood pressure from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Body temperature will be recorded throughout the hospitalization using a routine medical thermometer
Measure: Change of body temperature from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Oxygen partial pressure (pO2) will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of oxygen partial pressure (pO2) from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: CO2 partial pressure (pCO2) will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of CO2 partial pressure (pCO2) from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Blood pH will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of blood pH from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Bicarbonate will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of bicarbonate from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Base excess will be routinely assessed during the hospitalization in arterial or venous blood gas analyses
Measure: Change of base excess from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)Description: Oxygen flow rate will be routinely assessed during the hospitalization
Measure: Change of oxygen flow rate from baseline (hospitalization) to ICU admission Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)