Correlated Drug Terms (1)

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	Name (Synonyms)	Correlation
drug2145	SARS-Cov-2 infection Wiki	0.71

Correlated MeSH Terms (3)

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	Name (Synonyms)	Correlation
D016638	Critical Illness NIH	0.10
D045169	Severe Acute Respiratory Syndrome NIH	0.04
D018352	Coronavirus Infections NIH	0.03

Correlated HPO Terms (0)

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	Name (Synonyms)	Correlation

Primary Outcomes

Description: Highest level of mobility achieved at the point of ICU discharge

Measure: Mobility level

Time: At ICU discharge, an average of 3 weeks

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Description: Time taken to first mobilise, defined as sitting on the edge of the bed or higher

Measure: Time taken to first mobilise

Time: during ICU admission, up to 3 weeks

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Secondary Outcomes

Description: Discharged to home, home with rehab, or a community rehab facility

Measure: Discharge location

Time: Hospital discharge, up to 2 months

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Primary Outcomes

Description: The mMRC Dyspnea Scale is best used to establish baseline functional impairment due to dyspnea attributable to respiratory disease; tracking the mMRC over time or with therapeutic interventions is of less certain clinical utility.The severity of dyspnea is rated on a scale of 0 to 4. "O" means no dyspnea perception, "4" means severe dyspnea perception.

Measure: Modified Medical Research Council Dyspnea Score

Time: Baseline to 6 weeks

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Description: The Timed "Up and Go" (TUG) Test measures, in seconds, the time taken by an individual to stand up from a standard arm chair (approximate seat height of 46 cm, arm height 65 cm), walk a distance of 3 meters (approximately 10 feet), turn, walk back to the chair, and sit down. Normal healthy elderly usually complete the task in 10 seconds or less. Very frail or weak elderly with poor mobility may take 2 minutes or more. Clinical guide: <10 seconds = normal <20 seconds = good mobility, can go out alone, mobile without a gait aid <30 seconds = problems, cannot go outside alone, requires a gait aid A score of more than or equal to 14 seconds has been shown to indicate high risk of falls.

Measure: Timed up and go test

Time: Baseline to 6 weeks

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Description: Visual analog scale to assess the pain on a horizontal, non-calibrated line of 100 mm, ranging from very low (0) to very high (100)

Measure: Visual analog scale to assess the pain severity

Time: Baseline to 6 weeks

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Description: The Short Physical Performance Battery (SPPB) is comprised of 3 tasks: a standing balance test (side by side, semi-tandem and tandem), a 4-m habitual gait speed, and 5 sit to stand from a chair. Each task is scored (based on time) from 0-4 points. The total score is 12 points and this represents the highest performance. It can be easily performed at home via video conferencing

Measure: The Short Physical Performance Battery (SPPB)

Time: Baseline to 6 weeks

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Description: Visual analog scale to assess the fatigue severity on a horizontal, non-calibrated line of 100 mm, ranging from very low (0) to very high (100)

Measure: Visual analog scale to assess the fatigue severity

Time: Baseline to 6 weeks

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Secondary Outcomes

Description: This is a 21-item self-assessment scale designed by Aaron Beck in 1961 to measure the risk and level of depression.

Measure: BECK depression inventory

Time: Baseline to 6 weeks

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Description: The SGRQ ranges from 0 (no impairment of quality of life) to 100 (highest impairment of quality of life)

Measure: Saint George Respiratory Questionnaire

Time: Baseline to 6 weeks

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