There is one clinical trial.
The study will be a randomized controlled trial, involving patients with hyposmia/anosmia of onset immediately after an upper respiratory viral illness, assigned to three distinct study arms. Nasal irrigations will be prescribed to all three groups (BID). In addition, one arm will receive a paper hand-out about post-viral anosmia with instructions to smell common household items (current care) and act as a control group. The second group will receive an essential oil retraining kit, whereas the third group will receive the same olfactory training kit and a prescription to use budesonide with the nasal irrigations. Olfactory scores will be tested at the enrollment, 3 months and at 6 months.
Description: Score from the Snap and Sniff Olfactory Test results
Measure: Change from Baseline Snap and Sniff Threshold Test at 3 months Time: 3 monthsDescription: Score from the Smell Identification test results.
Measure: Change from baseline Smell Identification Test (SIT) at 3 months Time: 3 monthsDescription: Score from the Snap and Sniff Olfactory Test results
Measure: Change from Baseline Snap and Sniff Threshold Test at 6 months Time: 6 monthsDescription: Score from the Smell Identification test results.
Measure: Change from baseline Smell Identification Test (SIT) at 6 months Time: 6 monthsDescription: Scores from the short version of the Questionnaire of Olfactory Disorders Negative Statements (QOD-NS)
Measure: Change from baseline QOD-NS at 3 months Time: 3 monthsDescription: Short Form 36 Health Survey scores
Measure: Change from baseline SF-36 health survey at 3 months Time: 3 monthsDescription: Scores from the short version of the Questionnaire of Olfactory Disorders Negative Statements (QOD-NS)
Measure: Change from baseline QOD-NS at 6 months Time: 6 monthsDescription: Short Form 36 Health Survey scores
Measure: Change from baseline SF-36 health survey at 6 months Time: 6 monthsDescription: Adherence comparison between participants post-CoVID 19 and patients post other viral infections.
Measure: Adherence to the Study Protocol Time: 6 monthsDescription: Compare the rate of recovery between post-COVID 19 patients and patients post other viral infections.
Measure: Recovery Time: 6 months