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FolfirinoxWiki

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Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)

Name (Synonyms) Correlation
drug50 ABTL0812 Wiki 1.00
drug1822 Placebo Wiki 0.06

Correlated MeSH Terms (3)

Name (Synonyms) Correlation
D058186 Acute Kidney Injury NIH 0.24
D045169 Severe Acute Respiratory Syndrome NIH 0.05
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (1)

Name (Synonyms) Correlation
HP:0001919 Acute kidney injury HPO 0.24

There is one clinical trial.

Clinical Trials

1 A Phase I Open Label Followed by a Phase II Randomized, Controlled Study to Assess the Efficacy and Safety of ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic

A Phase I open label followed by a Phase II randomized, controlled study to assess the efficacy and safety of ABTL0812 in combination with FOLFIRINOX for first-line treatment of metastatic pancreatic

NCT04431258 Pancreatic Cancer Drug: ABTL0812 Drug: Folfirinox Drug: Placebo

Primary Outcomes

Description: Recommended Phase II Dose (RP2D) of ABTL0812 in combination with FOLFIRINOX

Measure: RP2D

Time: 6 months

Description: PFS using RECIST v1.1 by investigator analysis

Measure: PFS

Time: 1 year

Description: Objective response rate (ORR)

Measure: ORR

Time: 1 year

No related HPO nodes (Using clinical trials)