CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Counter Attitudinal TherapyWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug1237 Interpersonal Therapy Wiki 1.00

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D001068 Feeding and Eating Disorders NIH 0.50
D004194 Disease NIH 0.18

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Target Engagement of a Novel Dissonance-Based Treatment for DSM-5 Eating Disorders

Most people with an eating disorder (ED) do not receive good treatment. The investigators have developed a new brief group treatment that is supposed to work by reducing how much women with an ED value the impossible thinness standard promoted by the media and how much they value/crave binge foods. The investigators want to test whether the treatment actually changes those two mechanisms using brain scan data, which is more objective than completing questionnaires and even interviews. In the first phase of the study (R61), the investigators will compare women in the treatment versus those on a wait-list. If the investigators can show that the treatment "works" (does what the investigators think it does) compared to no active treatment (women will be allowed to seek and receive outside help but investigators will not provide it until after the wait-list), investigators will conduct the second phase of study (R33),where they will randomly assign women with an ED to either the new treatment or to a group treatment that represents what many college mental health clinics provide to their clients with ED.

NCT03261050 Eating Disorder Behavioral: Counter Attitudinal Therapy Behavioral: Interpersonal Therapy
MeSH:Disease Feeding and Eating Disorders

Primary Outcomes

Description: Interviewer assesses frequency in binge eating episodes

Measure: Change in occurrences of binge eating episodes using Eating Disorder Diagnostic Interview

Time: Week 8; R33 also reviews at 6-month follow-up

Description: Interviewer assesses frequency of compensatory weight control behaviors

Measure: Change in occurrences of compensatory weight control behavior using Eating Disorder Diagnostic Interview

Time: Week 8; R33 also reviews at 6-month follow-up

Description: Interviewer assesses change in psychosocial impairment

Measure: Change in psychosocial impairment due to eating disorder symptoms using the Clinical Impairment Assessment Questionnaire

Time: Week 8; R33 also reviews at 6-month follow-up

Secondary Outcomes

Description: Assess if CAT produces larger pre-post reductions in reward region in response to thin models and binge food (Not collected during COVID-19 shelter-at-home order)

Measure: Change in reward region of the brain using fMRI

Time: Week 1 and Week 8

Description: Assess if there are any changes in suicide ideation/attempts

Measure: Change in suicidal ideation/attempts using the Patient Health Questionnaire version 9 (PHQ-9)

Time: Weeks 2, 4 and 6

Description: Assess if there are any changes in negative affect

Measure: Change in negative affect using the Positive Affect and Negative Affect Scale-Revised

Time: Weeks 2, 4, and 6

Description: Assess if there are any changes in body dissatisfaction

Measure: Change in body dissatisfaction using the Body Dissatisfaction Scale

Time: Weeks 2, 4 and 6

Description: Assess if there are any changes in food addiction (Only collected during R61 phase)

Measure: Change in food addiction using the Yale Food Addiction Scale version 2.0

Time: Weeks 2, 4, and 6

Description: Assess if there are any changes in valuation of the thin beauty ideal

Measure: Change in valuation of thin ideal using the Thin Ideal Valuation Scale

Time: Weeks 2, 4, 6, and 8; R33 also reviews at 6-month follow-up

Description: Assess if there are any changes in dietary restraint

Measure: Change in dietary restraint using the 10-item Dutch Restrained Eating Scale

Time: Week 8; R33 also reviews at 6-month follow-up

Description: Three implicit association tasks will assess response to binge foods, thin models, and eating disorder behavior words at pre- and post-test (Not collected during COVID-19 shelter-at-home order)

Measure: Change in implicit associations of binge foods, thin models, and eating disorder behavior words

Time: Week 8; R33 also reviews at 6-month follow-up


No related HPO nodes (Using clinical trials)