Name (Synonyms) | Correlation | |
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drug1972 | Quantitative analysis of SARS-CoV-2 antibodies Wiki | 0.71 |
drug1973 | Quantitative analysis of anti-SARS-CoV-2-antibodies Wiki | 0.71 |
drug2942 | pathogen reduced SARS-CoV-2 convalescent plasma Wiki | 0.71 |
drug1822 | Placebo Wiki | 0.04 |
Name (Synonyms) | Correlation |
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There are 2 clinical trials
The aim of the SARS-CoV-2-CZ-Preval study is to quantify the prevalence of individuals with a history of SARS-CoV-2 coronavirus infection in the Czech population, except for those diagnosed with COVID-19 by methods based on direct detection of SARS-CoV- 2, including individuals with a subclinical course of the disease.
Description: Statistically, the primary objective is formulated as an estimate of the cumulative prevalence of SARS-CoV-2 positive individuals in geographically defined subpopulations of the Czech Republic with declared reliability of +/- 2%. For this primary objective, the required sample size in individual geographical cohorts is calculated. The positivity of SARS-CoV-2 individuals who have not been diagnosed with COVID-19 by a standard route of the detection will be assessed by the presence of specific IgM or IgG antibodies in the blood (antibody tests).
Measure: Estimation of the actual prevalence of SARS-CoV-2 positive persons in the Czech Republic. Time: May 2020Description: The proportion of SARS-CoV-2 positive persons who, according to the questionnaire, will not report any or minimal symptoms in the anamnesis.
Measure: Estimation of the proportion of people with a subclinical course of the disease Time: May 2020Description: The estimation will be calculated according to the prevalence of the disease in the population after excluding contraindications to blood donation (age, health status, etc.).
Measure: Estimation of the proportion of persons suitable for the donation of convalescent plasma Time: May 2020The aim of the SARS-CoV-2-CZ-Immunity study is to determine the time profile of the presence of antibodies against SARS-CoV-2 in blood plasma by quantification of antibodies or performing a rapid test in COVID-19 cured patients.
Description: The primary outcome is the determination of the concentration of anti-SARS-CoV-2 antibodies IgG, IgM, and IgA classes in relation to the categories of cured patients according to the time from the date of cure from the COVID-19 disease to the date of examination.
Measure: Determination of the concentration of anti-SARS-CoV-2 antibodies in relation to the categories of cured patients. Time: May 2020Description: The determination of the concentration of anti-SARS-CoV-2 antibodies IgG, IgM, and IgA classes in relation to the categories of cured patients according to their age: category 8-17, 18-39, 40-59, 60 and more years and according to the severity of the disease.
Measure: Determination of the concentration of anti-SARS-CoV-2 antibodies in relation to the age and to the severity of the disease. Time: June 2020Description: The quantification of the dependence of the change in the concentration of anti-SARS-CoV-2 antibodies IgG, IgM, and IgA classes on the time since cure (analysis by statistical model)
Measure: The quantification of the dependence of the change in the concentration of anti-SARS-CoV-2 antibodies. Time: June 2020Description: The identification of individuals in the study population, who can be contacted as voluntary donors of convalescent plasma, which is one of the therapeutic modalities in patients with severe COVID-19 disease.
Measure: The identification of potential donors of convalescent plasma. Time: June2020