Correlated Drug Terms (2)

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	Name (Synonyms)	Correlation
drug292	BIO101 Wiki	1.00
drug1822	Placebo Wiki	0.06

Correlated MeSH Terms (3)

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	Name (Synonyms)	Correlation
D055371	Acute Lung Injury NIH	0.10
D012127	Respiratory Distress Syndrome, Newborn NIH	0.10
D012128	Respiratory Distress Syndrome, Adult NIH	0.09

Correlated HPO Terms (0)

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	Name (Synonyms)	Correlation

Primary Outcomes

Description: Lung aeration measured by ultrasound reaeration score, ranges from 0 (all regions are well aerated) to 36 (all regions are consolidated).

Measure: Effects of a postural recruitment maneuver in lung aeration

Time: Through study completion (up to 24 hours)

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Description: Distribution of ventilation measured by EIT (distribution and changes in the impedance in AU, arbitray units)

Measure: Effects of a postural recruitment maneuver in distribution of ventilation

Time: Through study completion (up to 24 hours)

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Description: Gas exchange measured by blood gas analysis (PaO2, PaCO2, in mmHg) and capnography (end-tidal CO2, in mmHg)

Measure: Effects of a postural recruitment maneuver in gas exchange

Time: Through study completion (up to 24 hours)

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Description: Respiratory mechanics measured by esophageal balloon (esophageal pressure, transpulmonary pressure, in cmH2O)

Measure: Effects of a postural recruitment maneuver in respiratory mechanics

Time: Through study completion (up to 24 hours)

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Description: Hemodynamic data measured by invasive arterial monitoring (mean arterial pressure, in mmHg)

Measure: Effects of a postural recruitment maneuver in hemodynamic

Time: Through study completion (up to 24 hours)

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Secondary Outcomes

Description: Oxigenatory tolerance evaluated with pulse oximeter (arterial oxygen saturation, in percentage)

Measure: Feasibility of a postural recruitment maneuver

Time: Through study completion (up to 24 hours)

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