CovidResearchTrials by Shray Alag

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Mechanical ventilation with the automated BVM compressorWiki

Developed by Shray Alag
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There is one clinical trial.

Clinical Trials

1 A Repeated Measures Trial of Temporary Automated Manual Ventilation Versus Noninvasive Oxygenation or Conventional Ventilation for the Treatment of COVID-19 ARDS

The COVID-19 pandemic has led to a potential shortage of life-saving mechanical ventilators. The purpose of this study is to determine whether a novel simpler to device, the automated bag-valve-mask (BVM) compressor, can be used to provide assisted ventilation temporarily to patients in need. This includes patients with COVID-19 lung infection and respiratory failure. If successful, this would increase the pool of total available ventilator hours to alleviate any shortage.

NCT04369274 Respiratory Failure Device: Mechanical ventilation with the automated BVM compressor
MeSH:Respiratory Insufficiency

Primary Outcomes

Description: Arterial oxygenation obtained as measured by noninvasive pulse oximetry and arterial blood gas.

Measure: Arterial oxygenation

Time: Measurement 10 minutes after onset of initial period of automatic compressed ventilations

Description: Arterial oxygenation obtained as measured by noninvasive pulse oximetry and arterial blood gas.

Measure: Arterial oxygenation

Time: Measurement 20 minutes after onset of second period of automatic compressed ventilations

Secondary Outcomes

Description: Expired carbon dioxide (CO2) pressure will be measured continuously with a monitor in the airway circuit.

Measure: Expired pressure of carbon dioxide.

Time: 2 hour total study period.

Description: The pressure (cm H2O) of inspired and expired air in the airway circuit while the subject is mechanically ventilated will be measured continuously using a Nico monitor.

Measure: Airway pressure

Time: 2 hour total study period.

Description: Subject heart rate (beats per minute) will be measured continuously using a telemetry monitor,

Measure: Heart rate

Time: 2 hour total study period.

Description: Subject blood pressure (mm Hg) will be measured episodically every 5 minutes using an automated arm cuff.

Measure: Blood pressure

Time: 2 hour total study period.

Description: The flow (L/min) of inspired and expired air in the airway circuit while the subject is mechanically ventilated will be measured continuously using a Nico monitor.

Measure: Airway flow

Time: 2 hour total study period.

Other Outcomes

Description: The subject will be followed clinically to assess for recovery and survival or death.

Measure: Mortality

Time: Duration of hospitalization, up to 2 months

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