CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Self-guided exercisesWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug3023 telehealth applications Wiki 1.00
drug1747 PT-Pal Wiki 1.00

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D045169 Severe Acute Respiratory Syndrome NIH 0.05
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Home Based Covid-19 Rehabilitation Program: Pilot Clinical Trial

Our aim is to conduct a pilot single-blind randomized controlled trial to examine the preliminary efficacy of a 14 day app-based pulmonary and mobility focused rehabilitation program (intervention arm) versus a self-guided exercise program (active control arm) on pulmonary and functional outcomes in 100 patients tested for COVID-19 infection and isolated at home.

NCT04406532 Covid-19 Behavioral: PT-Pal Behavioral: Self-guided exercises

Primary Outcomes

Description: The SGRQ is a valid instrument for measuring pulmonary function in patients with respiratory disease, with a total score and scores for symptom, physical activity, and impact domains (range 0 to 100; higher scores worse). The minimum clinically important difference is 4 points. The questionnaire has excellent reliability and validity compared to gold standard pulmonary function tests.

Measure: Change in pulmonary function (St George's Respiratory questionnaire: SGRQ)

Time: baseline, at day 7 and at day 14

Description: The AM-PAC was developed to examine basic mobility and daily activity functional activities important to adults. It is a validated measure of patient-reported functional limitation in 3 domains: basic mobility, daily activities, and applied cognition. It is endorsed by the National Quality Forum as a functional status quality metric.

Measure: Change in physical function (Activity Measure for Post-Acute Care: AM-PAC)

Time: baseline, at day 7 and at day 14

Secondary Outcomes

Description: Patient asked to take a deep breath while at rest and to hold it (Normal >25 s). Test monitored by video (Zoom, PT-Pal).

Measure: Change in pulmonary function (Sabrasez single breath count)

Time: baseline, at day 7 and at day 14

Description: Participants will be given a peak flow meter at recruitment, and taught how to use it by research staff over video.

Measure: Change in pulmonary function (Peak flow tests)

Time: baseline, at day 7 and at day 14

Description: This timed test assesses strength, balance and endurance. Test monitored by video (Zoom, PT-Pal).

Measure: Change in physical function (5 times site to stand test)

Time: baseline, at day 7 and at day 14

Description: Self-report or information from medical staff.

Measure: Health events (emergency room visits and hospitalizations)

Time: baseline to day 14

Description: Anxiety symptoms reported on the BAI. Higher scores indicate more anxiety.

Measure: Change in psychological measures (Beck Anxiety Inventory: BAI)

Time: baseline, at day 7 and at day 14

Description: Depressive symptoms reported on the CES-D. Higher score indicate more depressive symptoms.

Measure: Change in psychological measures (Center for Epidemiologic Studies Depression Scale: CES-D)

Time: baseline, at day 7 and at day 14

Description: Number of sessions completed using app in the intervention arm. Controls periodically interviewed.

Measure: Feasibility (Adherence)

Time: baseline to day 14

Description: Survey of satisfaction with exercise programs.

Measure: Feasibility (Acceptability)

Time: baseline to day 14


No related HPO nodes (Using clinical trials)