Name (Synonyms) | Correlation |
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Name (Synonyms) | Correlation | |
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D015428 | Myocardial Reperfusion Injury NIH | 1.00 |
D015427 | Reperfusion Injury NIH | 1.00 |
D014947 | Wounds and Injuries NIH | 0.22 |
D002318 | Cardiovascular Diseases NIH | 0.21 |
Name (Synonyms) | Correlation | |
---|---|---|
HP:0001626 | Abnormality of the cardiovascular system HPO | 0.21 |
There is one clinical trial.
Little is known about the physical function outcomes in patients with severe COVID-19 patients who are admitted to Intensive Care Unit (ICU) for invasive mechanical ventilation. The purpose of this study is to evaluate the short-term impact on physical function before hospital discharge in subjects with severe COVID-19 who have survived ICU admission for invasive mechanical ventilation.
Description: Physical examination will be performed to carry out manual muscle testing of strength in 6 different muscle groups of the upper limb and lower limb on both sides of the body.
Measure: Medical Research Council sum score (MRC- SS). Time: < 48 hours before ICU dischargeDescription: Physical examination will be performed to carry out manual muscle testing of strength in 6 different muscle groups of the upper limb and lower limb on both sides of the body.
Measure: Medical Research Council sum score (MRC- SS). Time: < 24 hours before hospital dischargeDescription: The Functional Status Score for the ICU (FSS-ICU) will be used to evaluate 5 functional tasks. Each task is evaluated using an 8-point ordinal scale ranging from 0 (not able to perform) to 7 (complete independence).The total FSS-ICU score ranges from 0 to 35, with higher scores indicating better physical functioning.
Measure: The Functional Status Score for the ICU (FSS-ICU) Time: < 24 hours before hospital dischargeDescription: Age in years
Measure: Age Time: Through study completion, up to 6 monthsDescription: Male vs Female
Measure: Sex Time: Throughout study completion , up to 6 monthDescription: kg/m2
Measure: Body Mass Index Time: Throughout study completion, up to 6 monthsDescription: Baseline mobility
Measure: Baseline mobility Time: First day the patient can cooperate with assessment according to the ' 5 Standard Questions' test.Description: Acute Physiology and Chronic Health Evaluation II score.The APACHE II score ranges from 0 to 71 points. Higher scores correspond to more severe disease and a higher risk of death.
Measure: APACHE II score Time: <24 hours after ICU admissionDescription: Number of days of stay in ICU
Measure: Length of stay in ICU Time: Throughout the study completion, up to 6 monthsDescription: Number of days on mechanical ventilation
Measure: Number of days on mechanical ventilation Time: Throughout the study completion, up to 6 monthsDescription: Clinical or EMG polyneuropathy diagnosis confirmation
Measure: Polyneuropathy diagnosis Time: Throughout the study completion, up to 6 monthsDescription: Number of days on NMB during mechanical ventilation
Measure: Number of days on Neuromuscular Blockers Time: Throughout the study completion, up to 6 monthsDescription: Number of prone positioning episodes during ICU stay
Measure: Episodes of prone positioning Time: Throughout the study completion, up to 6 monthsDescription: Total number of days admitted to hospital
Measure: Length of stay in hospital Time: Throughout the study completion, up to 6 monthsDescription: Home with no follow-up physiotherapy, home with domiciliary or out-patient physiotherapy, rehabilitation facility, care home, transfer to another acute hospital.
Measure: Continuation of care Time: Throughout the study completion, up to 6 months