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Asynchronies detectionWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug902 Extracorporeal membrane oxygenation Wiki 1.00

Correlated MeSH Terms (4)


Name (Synonyms) Correlation
D013577 Syndrome NIH 0.11
D055371 Acute Lung Injury NIH 0.10
D012127 Respiratory Distress Syndrome, Newborn NIH 0.10
D012128 Respiratory Distress Syndrome, Adult NIH 0.09

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Characterization of Reverse Triggering and Other Asynchronies in COVID-19 Patients Under Invasive Mechanical Ventilation

Prospective observational trial in patients admitted to ICU diagnosed with COVID-19 requiring invasive mechanical ventilation. Characterization of Reverse Triggering asynchrony during the first 5 days of invasive mechanical ventilation and other asynchronies, and its correlation with different outcomes.

NCT04448782 Mechanical Ventilation Complication Diagnostic Test: Asynchronies detection

Primary Outcomes

Description: To analyze the incidence of Reverse Triggering in the initial phases of invasive mechanical ventilation in COVID-19 patients

Measure: Incidence and pattern of presentation of Reverse triggering in COVID-19 patients under invasive mechanical ventilation

Time: during the 5 first days of invasive mechanical ventilation

Secondary Outcomes

Description: To correlate the presence of Reverse Triggering with the level of sedation and use of neuromuscular blockers

Measure: Incidence of Reverse Triggering related to the level of sedation in COVID-19 patients under invasive mechanical ventilation

Time: From the day of mechanical ventilation initation up to 5 days or the last day of mechanical ventilation

Description: To analyze the incidence of breath stacking and ineffective efforts secondary to RT.

Measure: Reverse triggering and secondary asynchronies in COVID-19 patients under invasive mechanical ventilation

Time: From the day of mechanical ventilation initiation up to 5 days

Description: To analyze the incidence of RT, ineffective efforts and double triggering throughout the period of invasive mechanical ventilation

Measure: Incidence and pattern of presentation of asynchronies in COVID-19 patients under invasive mechanical ventilation

Time: Each day from the day of mechanical ventilation initiation until the day of mechanical ventilation withdrawal or up to 28 days

Description: To correlate the presence of asycnhronies and its type with duration of invasive mechanical ventilation, ICU length of stay and survival

Measure: Influence of asynchronies in different outcomes in in COVID-19 patients under invasive mechanical ventilation

Time: Each day from the day of mechanical ventilation initiation until the end of invasive mechanical ventilation, ICU discharge and hospital discharge or up to 28 days


No related HPO nodes (Using clinical trials)