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ELMO PROJECT AT COVID-19: PROOF OF CONCEPT AND USABILITYWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug813 ELMO PROJECT AT COVID-19: STUDY IN HUMANS Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D000860 Hypoxia NIH 0.23

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0012418 Hypoxemia HPO 0.23

There is one clinical trial.

Clinical Trials


1 Elmo Respiratory Support Project for Patients With Hypoxemic Respiratory Insufficiency in Covid-19: Proof Of Concept and Usability

The number of COVID-19 cases has been growing exponentially, so that the industrialized economies are facing a significant shortage in the number of ventilators available to meet the demands imposed by the disease. Noninvasive ventilatory support can be valuable for certain patients, avoiding tracheal intubation and its complications. However, non-invasive techniques have a high potential to generate aerosols during their implementation, especially when masks are used in which it is virtually impossible to completely prevent air leakage and the dispersion of aerosols with viral particles. In this context, a helmet-like interface system with complete sealing and respiratory isolation of the patient's head can allow the application of ventilatory support without intubation and with safety and comfort for healthcare professionals and patients. This type of device is not accessible in Brazil, nor is it available for immediate import, requiring the development of a national product. Meanwhile, a task force under the coordination of the School of Public Health (ESP) and Fundação Cearense de Apoio à Pesquisa (FUNCAP), with support from SENAI / FIEC and the Federal Universities of Ceará (UFC) and the University of Fortaleza (UNIFOR) advanced in the development of a prototype and accessory system capable of providing airway pressurization through a helmet-type interface, which was called the Elmo System.

NCT04470258 COVID-19 Respiratory Failure With Hypoxia Other: ELMO PROJECT AT COVID-19: STUDY IN HUMANS Device: ELMO PROJECT AT COVID-19: PROOF OF CONCEPT AND USABILITY
MeSH:Respiratory Insufficiency Hypoxia
HPO:Hypoxemia

Primary Outcomes

Description: Usability test with the description of the identified problems of the main basic skills necessary for the correct handling of the non-invasive respiratory device (ELMO), through realistic simulations, severity scale and usability.

Measure: Usability tests of the Elmo system using Euristic usability principles

Time: One week after all tests

Description: To evaluate the effectiveness of the Elmo system in the supportive treatment of patients with hypoxemic respiratory failure caused by COVID-19 through peripheral oxygen saturation (%) before, during and after the application of Elmo.

Measure: Evaluation of the effectiveness of the ELMO system using physiological parameters

Time: One week after all tests

Secondary Outcomes

Description: To evaluate the effectiveness of the Elmo system in the supportive treatment of patients with hypoxemic respiratory failure caused by COVID-19 through respiratory rate (irpm) before, during and after the application of Elmo.

Measure: Evaluation of the effectiveness of the ELMO system using physiological parameters

Time: One week after all tests

Description: To evaluate the effectiveness of the Elmo system in the supportive treatment of patients with hypoxemic respiratory failure caused by COVID-19 through heart rate before, during and after the application of Elmo.

Measure: Evaluation of the effectiveness of the ELMO system using physiological parameters

Time: One week after all tests

Description: To evaluate the effectiveness of the Elmo system in the supportive treatment of patients with hypoxemic respiratory failure caused by COVID-19 through blood pressure before, during and after the application of Elmo.

Measure: Evaluation of the effectiveness of the ELMO system using physiological parameters

Time: One week after all tests

Description: To evaluate the effectiveness of the Elmo system in the supportive treatment of patients with hypoxemic respiratory failure caused by COVID-19 through CO2 measurement at the end of exhalation (mmHg) before, during and after the application of Elmo.

Measure: Evaluation of the effectiveness of the ELMO system using physiological parameters

Time: One week after all tests


Related HPO nodes (Using clinical trials)