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100 mg/mL VirazoleWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug44 50 mg/mL Virazole Wiki 1.00
drug1613 No intervention Wiki 0.24

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D000163 Acquired Immunodeficiency Syndrome NIH 0.58
D015658 HIV Infections NIH 0.41

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 An Open-Label Study to Evaluate the Safety and Efficacy of VIRAZOLE® (RIBAVIRIN FOR INHALATION SOLUTION, USP) in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19

This study is a Phase 1, open label, non-randomized, two-arm interventional clinical trial to evaluate the safety and efficacy of Virazole® in hospitalized adult patients who have tested positive for COVID-19 and, as a result, have significant respiratory distress (PaO2/FiO2 ratio <300 mmHg).

NCT04356677 COVID19 Drug: 50 mg/mL Virazole Drug: 100 mg/mL Virazole

Primary Outcomes

Description: The severity rating will be based on the ordinal scale of clinical status as follows: Death. Hospitalized, on invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO). Hospitalized, on non-invasive ventilation or high flow oxygen devices. Hospitalized, requiring supplemental oxygen. Hospitalized, not requiring supplemental oxygen. Not hospitalized, limitation on activities. Not hospitalized, no limitations on activities.

Measure: Change in the clinical status severity (CSS) rating from the first dose date up to the completion of treatment

Time: 7 days

Secondary Outcomes

Measure: Time to recover gas exchange to a PaO2/FiO2 ≥300 for at least 24 hours.

Time: 7 days

Measure: Time to reach peripheral capillary oxygen saturation (Sp02) >94% for at least 24 hours.

Time: 7 days


No related HPO nodes (Using clinical trials)