CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Sildenafil citrate tabletsWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug1365 Lopinavir-Ritonavir Wiki 0.71
drug1086 Hydroxychloroquine Wiki 0.10

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D045169 Severe Acute Respiratory Syndrome NIH 0.05
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 A Pilot Study of Sildenafi in the Treatment of COVID-19

Observe the efficacy and safety of G1(Sildenafil citrate tablets) in patients with COVID-19 under clinical actual diagnosis and treatment conditions

NCT04304313 COVID-19 Drug: Sildenafil citrate tablets

Primary Outcomes

Description: fever,cough and other symptoms relieved with improved lung CT; SPO2>93% or PaO2/FiO2 >300mmHg without oxygen inhalation.

Measure: Rate of disease remission

Time: 14 days

Description: Comply with any of the followings: Respiratory failure occurs and requires mechanical ventilation; Shock; Patients combined with other organ failure need ICU monitoring and treatment.

Measure: Rate of entering the critical stage

Time: 14 days

Description: Comply with any of the followings: Respiratory failure occurs and requires mechanical ventilation; Shock; Patients combined with other organ failure need ICU monitoring and treatment.

Measure: Time of entering the critical stage

Time: 14 days

Secondary Outcomes

Measure: Rate of no fever

Time: 14 days

Measure: Rate of respiratory symptom remission

Time: 14 days

Measure: Rate of lung imaging recovery

Time: 14 days

Measure: Rate of C-reactive protein (CRP) recovery

Time: 14 days

Measure: Rate of Biochemical criterion (CK, ALT, Mb) recovery

Time: 14 days

Measure: Rate of undetectable viral RNA (continuous twice)

Time: 14 days

Description: From the date of enrollment to the time when the subject is released from the hospital or transferred to the corresponding department for treatment of other diseases according to the condition.

Measure: Time for hospitalization

Time: 14 days

Description: All adverse events will be coded and described using the International Medical Terms Dictionary (MedDRA).

Measure: Rate of adverse event

Time: 14 days


No related HPO nodes (Using clinical trials)