Correlated Drug Terms (1)

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	Name (Synonyms)	Correlation
drug2542	Tracheotomy Wiki	1.00

Correlated MeSH Terms (3)

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	Name (Synonyms)	Correlation
D011665	Pulmonary Valve Insufficiency NIH	0.41
D045169	Severe Acute Respiratory Syndrome NIH	0.05
D018352	Coronavirus Infections NIH	0.04

Correlated HPO Terms (1)

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	Name (Synonyms)	Correlation
HP:0010444	Pulmonary insufficiency HPO	0.41

Primary Outcomes

Description: Number of participants that require ECMO Number of participants that cannot be extubated within 10 days or A downward change in Oxygenation Index by >15% from baseline

Measure: Reduction in Respiratory Failure

Time: 10 days

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Description: Number of participants that require ECMO Number of participants requiring inotropic therapy Number of participants that require mechanical circulatory support A change in Cardiac Troponin >20% from baseline or A change in BNP >15% from baseline

Measure: Reduction in Cardiac/Circulatory Failure

Time: 10 days

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Secondary Outcomes

Description: Number of participants that demonstrate a change in FiO2 by 50% or more.

Measure: Improvement in Oxygenation

Time: 10 days

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Description: Number of participants with a reduction in the time to extubation Number of participants with a reduction in ICU days Number of participants with a reduction in hospital days

Measure: Improved Clinical Outcomes

Time: 28 days

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