CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Algorithm-based recommendationWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (4)


Name (Synonyms) Correlation
drug2100 Risk reduction Wiki 1.00
drug1452 Medical records-based recommendation Wiki 1.00
drug1473 Mesenchymal Stromal Cells Wiki 0.58
drug2381 Supportive Care Wiki 0.58

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D055371 Acute Lung Injury NIH 0.10
D012127 Respiratory Distress Syndrome, Newborn NIH 0.10
D012128 Respiratory Distress Syndrome, Adult NIH 0.09

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Encouraging Flu Vaccination Among High-Risk Patients Identified by a Machine-Learning Model of Flu Complication Risk

The purpose of the current study is to test different interventions to determine the most effective way to promote flu vaccine uptake in a high-risk population identified by an "artificial intelligence" (AI) or machine learning (ML) algorithm. The specific aims are: 1. Evaluate the effect on flu vaccination rates of informing health-system patients who are identified by an ML analysis of EHR data to be at high risk for flu complications that they are at high risk with either (a) no additional explanation, (b) an explanation that this determination comes from an analysis of their medical records, and (c) the additional explanation that an AI or ML algorithm made this determination. 2. Evaluate the effects of the same three interventions on diagnoses of flu in the same patients.

NCT04323137 Influenza Vaccination Health Promotion Health Behavior Risk Reduction Behavioral: Risk reduction Behavioral: Medical records-based recommendation Behavioral: Algorithm-based recommendation

Primary Outcomes

Description: Patient received a flu vaccination

Measure: Flu vaccination rate

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Description: Patient received a flu diagnosis

Measure: Flu diagnosis rate

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Secondary Outcomes

Description: Patient was diagnosed with flu-like symptoms

Measure: Flu-like symptoms rate

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Description: Patient was diagnosed with flu-related complications

Measure: Flu complications rate

Time: Through 3 months after the end of the flu season (August 31st 2021), approximately 12 months assessment duration

Description: Number of patient visits to the ER, examining relative rate of visits across Time 1 and 2

Measure: Change in ER visits from pre- to post-intervention

Time: Within 12 months pre-intervention (Time 1) and within 12 months post-intervention (Time 2)

Description: Number of patient hospital visits, examining relative rate of visits across Time 1 and 2

Measure: Change in hospitalizations from pre- to post-intervention

Time: Within 12 months pre-intervention (Time 1) and within 12 months post-intervention (Time 2)

Description: Non-targeted fellow household members of targeted patients received a flu vaccination

Measure: Flu vaccination among fellow household members

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Description: Non-targeted fellow household members of targeted patients received a flu diagnosis

Measure: Flu diagnosis among fellow household members

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Description: Non-targeted fellow household members of targeted patients were diagnosed with flu-like symptoms

Measure: Flu-like symptoms among fellow household members

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Description: Non-targeted fellow household members of targeted patients were diagnosed with flu-related complications

Measure: Flu complications among fellow household members

Time: Through 3 months after the end of the flu season (August 31st 2021), approximately 12 months assessment duration

Description: Non-targeted sub-threshold risk patients received a flu vaccination

Measure: Flu vaccination among those at sub-threshold risk

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Description: Non-targeted sub-threshold risk patients received a flu diagnosis

Measure: Flu diagnosis among those at sub-threshold risk

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Description: Non-targeted sub-threshold risk patients were diagnosed with flu-like symptoms

Measure: Flu-like symptoms among those at sub-threshold risk

Time: Through the the end of the flu season (May 31st 2021), approximately 9 months assessment duration

Description: Non-targeted sub-threshold risk patients were diagnosed with flu-related complications

Measure: Flu complications among those at sub-threshold risk

Time: Through 3 months after the end of the flu season (August 31st 2021), approximately 12 months assessment duration


No related HPO nodes (Using clinical trials)