CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


COVID-19 barrier boxWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug477 COVID-19 infection Wiki 1.00

Correlated MeSH Terms (8)


Name (Synonyms) Correlation
D001167 Arteritis NIH 0.71
D011111 Polymyalgia Rheumatica NIH 0.58
D013700 Giant Cell Arteritis NIH 0.58
D003095 Collagen Diseases NIH 0.50
D015535 Arthritis, Psoriatic NIH 0.50
D012216 Rheumatic Diseases NIH 0.45
D008180 Lupus Erythematosus, Systemic NIH 0.41
D001168 Arthritis NIH 0.29

Correlated HPO Terms (3)


Name (Synonyms) Correlation
HP:0012089 Arteritis HPO 0.71
HP:0002725 Systemic lupus erythematosus HPO 0.41
HP:0001369 Arthritis HPO 0.29

There is one clinical trial.

Clinical Trials


1 The Impact of a Barrier Enclosure on Endotracheal Intubation Duration and First Pass Attempt - A Randomized Controlled Trial

The trial will be done to determine the impact of a barrier enclosure, COVID (coronavirus disease -19) barrier box on endotracheal intubation attempts, and duration. This study will be a prospective, open-label, randomized controlled trial. A total of 100 patients scheduled for elective surgery will be randomly assigned in two groups (intervention group and control group). Participating attending anesthesiologists will intubate the intervention group patients with COVID barrier box and the control group patients without the box. The anesthesiologists and the intervention group patients will be surveyed about their perception after the surgery. The result of this study will help in decision making about using COVID barrier box to minimize the viral transmission from patients to healthcare workers during the pandemic.

NCT04366141 COVID-19 Device: COVID-19 barrier box

Primary Outcomes

Description: TTI is the time from when the laryngoscope blade passes between the patient's lips until the first upstroke of the capnograph trace. TTI will be measured by a third party observer outside of the operating room.

Measure: Time to tracheal intubation (TTI)

Time: This will be measured at the time of intubation for an elective surgical patient. It will take approximately 5 minutes.

Secondary Outcomes

Description: A first pass success refers to successful insertion of the McGRATH™ videolaryngoscope or endotracheal tube by an anesthesiologist on the first-attempt without withdrawing from the mouth in no longer than 150 seconds.

Measure: First pass success rate

Time: This will be measured at the time of intubation for an elective surgical patient within 150 seconds of initiating the first attempt to intubate.

Description: This refers to the time from the face mask seal being lifted to the first upstroke of the capnograph trace.

Measure: Total time of airway manipulation

Time: This will be measured at the time of intubation for an elective surgical patient. It will take approximately 5 minutes.

Description: Participant anesthesiologists will report the number of intubation attempts that were needed to achieve successful intubation.

Measure: Number of intubation attempts

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Participant anesthesiologists will report the number of operators needed to assist in successfully intubating the participant.

Measure: Number of Operators needed for intubation

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Participant anesthesiologists will report the number of alternative techniques used for intubation (if any) i.e. repositioning of patient, change of materials (blade, endotracheal (ET) tube, addition of stylette), change in approach (nasotracheal vs orotracheal), use of another technique (Fibreoptic bronchoscopy, intubating laryngeal mask airway (LMA)

Measure: Number of alternative techniques used for intubation

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Participant anesthesiologists will report the Cormack-Lehane Grade for the first attempt of intubation.

Measure: Cormack-Lehane Grade for the first attempt of intubation

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Participant anesthesiologists will report if the lifting force applied on laryngoscope blade was normal or increased.

Measure: Lifting force applied on laryngoscope blade

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Participant anesthesiologists will report if laryngeal pressure, such as Backward Upward Rightward Pressure (BURP) not inclusive of cricoid pressure was applied or not.

Measure: Laryngeal pressure application

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Participant anesthesiologists will report the vocal cord position (either abduction or adduction).

Measure: Vocal cord position

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Participant anesthesiologists will report the difficulty experienced during the intubation from a scale of 0 to 10 with 0 being without difficulty and 10 being maximum difficulty.

Measure: Anesthesiologist perception of intubation difficulty

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Participant anesthesiologists will report any contributors to difficulties in intubation, or state "none", if no difficulties were experienced.

Measure: Anesthesiologist perception of contributors to difficulty in intubation, if any

Time: This will be filled out as part of a questionnaire after intubation is completed. It will take approximately 10 minutes to complete the full questionnaire..

Description: Patients from the intervention group will report the acceptability of COVID barrier box. They will be asked "How acceptable did you find the use of the COVID barrier box?" and respond on a five-point scale (acceptable, slightly acceptable, neutral, slightly unacceptable, unacceptable).

Measure: Patient acceptability of the COVID Barrier Box

Time: This question will be asked as part of a short questionnaire administered to patients when they meet the Post Anesthesia Care Unit (PACU) discharge criteria (usually 2 to 5 hours after surgery). It will take about 10 minutes to complete.

Description: Patients from the intervention group will report their level of comfort experienced with the use of the COVID barrier box. They will be asked "How comfortable did you find the use of the COVID barrier box?" and will respond on a five-point scale (comfortable, slightly comfortable, neither, slightly uncomfortable, uncomfortable).

Measure: Patient comfort with the COVID Barrier Box

Time: This question will be asked as part of a short questionnaire administered to patients when they meet the Post Anesthesia Care Unit (PACU) discharge criteria (usually 2 to 5 hours after surgery). It will take about 10 minutes to complete.

Description: Patients from the intervention group will report any comments that they have on the COVID barrier box.

Measure: Patient comments on the COVID Barrier Box

Time: This question will be asked as part of a short questionnaire administered to patients when they meet the Post Anesthesia Care Unit (PACU) discharge criteria (usually 2 to 5 hours after surgery). It will take about 10 minutes to complete.


No related HPO nodes (Using clinical trials)