CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

Questionnaire by phone callWiki

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Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)

Name (Synonyms) Correlation
drug473 COVID-19 diagnostic test Wiki 1.00

Correlated MeSH Terms (5)

Name (Synonyms) Correlation
D012859 Sjogren's Syndrome NIH 0.71
D001327 Autoimmune Diseases NIH 0.58
D015535 Arthritis, Psoriatic NIH 0.50
D008180 Lupus Erythematosus, Systemic NIH 0.41
D001168 Arthritis NIH 0.29

Correlated HPO Terms (3)

Name (Synonyms) Correlation
HP:0002960 Autoimmunity HPO 0.58
HP:0002725 Systemic lupus erythematosus HPO 0.41
HP:0001369 Arthritis HPO 0.29

There is one clinical trial.

Clinical Trials

1 Association Between Long-term Hydroxychloroquine Treatment and Outcome of a History of Symptoms Suggestive of COVID-19 Infection During the Epidemic Period in France in Patients With Autoimmune Disease

This epidemiological, transversal, cohort study aims to determine the potential influence of an active long-term hydroxychloroquine intake over the prevalence of a history of symptoms evocative of a COVID-19 infection in patients with a history of systemic lupus erythematosus, rheumatoid arthritis, Sjogren's syndrome or psoriatic arthritis, during the epidemic period in France. The information is gathered using a standardized questionnaire, by phone call.

NCT04345159 SARS-CoV-2 Systemic Lupus Erythematosus Rheumatoid Arthritis Sjogren's Syndrome Psoriatic Arthritis Other: Questionnaire by phone call
MeSH:Arthritis Arthritis, Psoriatic Sjogren's Syndrome Lupus Erythematosus, Systemic Autoimmune Diseases
HPO:Arthritis Autoimmunity Polyarticular arthritis Systemic lupus erythematosus

Primary Outcomes

Description: Adjusted Odds Ratio measuring the association between an exposure to long-term hydroxychloroquine intake and a history of symptoms compatible with a COVID-19 infection.

Measure: Adjusted Odds Ratio

Time: 4 months after inclusion

Related HPO nodes (Using clinical trials)

HP:0001369: Arthritis
Genes 263
CCN6 IL2RA NFKBIL1 LBR SPTB BLNK TRAPPC2 EPB42 MVK CD79A IL36RN COMP STAT3 IL2RB TGFB3 MEFV IL12A-AS1 CASP10 MLX MMP13 SLCO2A1 COL2A1 COL2A1 ASAH1 IGHM COL2A1 APOE HNF4A COL2A1 ADA2 PTPN22 MMP14 NOD2 CD247 BTK SCARB2 COL2A1 GLA UMOD CCR1 COL11A2 LRBA CCR6 COMP EXT1 IL6 RREB1 KLRC4 COL11A1 PTPN22 PSTPIP1 HNF1B SAMHD1 HLA-C COL11A2 LRP6 GPR101 COL2A1 RAG1 KIF7 DCLRE1C NOD2 CTLA4 NLRP3 HPRT1 ABCG8 HGD MMP13 HLA-DRB1 NLRP3 SH3KBP1 SLC37A4 TF CCN6 ZNF687 GJB2 IL2RA PFKM AIP FASLG TREX1 HLA-B MATN3 ASPN TNFRSF1A C4A COL2A1 MYH14 UBAC2 FAS ARVCF ACP5 EXT2 PRG4 AEBP1 MTHFD1 ANKRD55 PTPN22 TFR2 GCH1 GJB6 COL9A1 COL11A2 PTPN22 SPP1 RNASEH2B TRAPPC2 OCRL TREX1 LRRC8A GBA COL1A1 LMX1B ACAN GP1BB TLR4 ANK1 COMP UFD1 SLC12A3 NLRP3 FAS HGD IL12A SEC61A1 PHEX COPA HPGD IRF5 FCGR2B TRPV4 PSMB9 WIPF1 CTLA4 CAV1 MVK HLA-DRB1 ATP7B MUC1 COL9A1 ACAN ATP7B EPCAM DNASE1L3 CLCNKB LMNA MMP2 IL10 IL12B RASGRP1 PTPN2 COMT COL2A1 STAT4 SLC37A4 GNAS MIF HLA-DRB1 WAS STAT4 RNF168 CLCN7 JMJD1C IL23R MEFV G6PC CFI ERAP1 F8 PSTPIP1 GHR HLA-B HIRA PRPS1 ADAR DNAJB11 MEFV PTPN2 IL10 ANKH IFIH1 STAT4 COL5A1 FRZB HPGD KIF22 TBX1 CIITA CD79B IGLL1 IRAK1 IL2RB MATN3 COL9A2 COL9A3 TNFRSF11B COMP HLA-B STAT4 PADI4 MATN3 HJV COL2A1 SMAD3 F9 TRPS1 UFSP2 RAG2 COL1A1 MEFV COL5A1 ANKRD55 SLC40A1 SLC4A1 SPTA1 FBN1 BTK RNASEH2C DNASE1 CANT1 TBX1 PHEX CD247 TCF3 PSMB4 PIK3R1 AGA CD244 COL5A2 LEMD3 FGFR3 RNASEH2A ACAN HPRT1 ANKH SEC24C GDF5 SLC22A4 UMOD HPRT1 TRPV4 HPGD BTK FAS COL9A3 UFSP2 ZMPSTE24 PTPN22 LACC1 HPRT1 NLRP3 HNF1B HOXD10 PRKCD SLC26A2 COL9A2 SMAD3 FCGR2A CCN2 CLCN7 COL3A1 ASAH1 NLRP12
Protein Mutations 4
A147T N363S R620W V600E
SNP 10
rs2246704 rs2853884 rs35705950 rs3747158 rs3790515 rs3828057 rs4820059 rs7291050 rs933226 rs9826
HP:0002960: Autoimmunity
Genes 218
KMT2D IL2RA ARHGEF1 NHEJ1 STAT3 IL2RB CD19 C1QA CASP10 CTLA4 C4A TTC7A GPR35 CD81 PNP RAG2 ADA2 SERPING1 PTPN22 CD247 SERPING1 LRBA CCR6 TTC7A CD19 IL6 RREB1 PTPN22 SAMHD1 TNFRSF13B TCF4 SEC23B FADD DCLRE1C PLCG2 CTLA4 HLA-DRB1 ICOS NRAS TNFRSF13C HLA-DRB1 MMP2 RFXAP LIG4 TRAC IL7R IL2RA LACC1 IRF5 CSF2RB FLT1 FASLG CD3G HAVCR2 TREX1 SMPD1 KIAA0319L CORIN FAS IL6 ARVCF ACP5 ZAP70 RAG2 C1R NFKB2 MST1 MTHFD1 ADA ANKRD55 RAG1 TPP2 ITCH CSF2RA PTPN22 TNFAIP3 FAS TBX2 SPP1 TNPO3 RNASEH2B TREX1 PNP HLA-DPB1 ZAP70 HLA-DPA1 TREX1 SERPING1 DCLRE1C GP1BB UFD1 ADA SLC12A3 ICOS GFI1 FOXP3 PTPN22 SPIB ICOS C2 IRF5 FCGR2B PIK3R1 ELANE WIPF1 SRP54 CTLA4 NFKB1 CAV1 STAT1 PAX4 HLA-DRB1 PTEN CASP10 TNFRSF13B ADA2 DNASE1L3 STIM1 CLCNKB DNASE1L3 GALC MS4A1 NLRP1 IFNGR1 CTLA4 RASGRP1 PTPN2 COMT RAG1 STAT4 MIF AIRE WAS RMRP HLA-DRB1 JMJD1C POU2AF1 C1GALT1C1 TNFRSF13C C1QC HIRA ADAR PTPN2 IFIH1 STAT4 PTPN22 PGM3 POLG C8A TBX1 ITCH CHD7 IRAK1 PRTN3 IL12A FOXD3 TNFRSF13B IL2RB ITPR3 TCIRG1 IL7R CR2 IL2RG STAT4 IL2RB ANKRD55 CCN2 FOXP3 IL12RB1 LMNB2 PRKCD RFXANK RNASEH2C DNASE1 C1S FASLG DDX41 MASP2 HNF1A TBX1 CAV1 CD247 MMEL1 CIITA TNFSF12 STOX1 ITK IRF5 RNASEH2A CR2 IL2RA LCK HLA-DQB1 SLC7A7 NBN SEC24C C1QB NFKB2 ADA TNFSF12 BTK PEPD FAS CCR6 LACC1 NBN C3 PRKCD TNFSF15 RFX5 PRKCD ADA2 FCGR2A CCN2 STAT1 KDM6A RAG1 KRAS
Protein Mutations 3
D89E S1009A V600E
SNP 0
HP:0005764: Polyarticular arthritis
Genes 13
ANKRD55 CD247 STAT4 NOD2 NLRP1 IL2RA DMP1 ENPP1 TNFAIP3 MEFV IL2RB PTPN2 PTPN22
Protein Mutations 0
SNP 0
HP:0002725: Systemic lupus erythematosus
Genes 31
TPP2 C2 FCGR2B C1QB C1QC CTLA4 PTPN22 SPP1 PEPD FAS FASLG SMPD1 TREX1 C3 SERPING1 C1QA CASP10 DNASE1 C1S FAS PRKCD DNASE1L3 DDX41 C8A MASP2 FCGR2A RASGRP1 C4A STAT4 IRAK1 PNP
Protein Mutations 1
V600E
SNP 0