CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Reinforcement learning message deliveryWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug2599 Uniform random message delivery Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D003863 Depression, NIH 0.15

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Stay Well at Home: A Text-messaging Study to Improve Mood and Help Cope With Social Distancing

The investigators have developed supportive text-messages in English and Spanish to help people cope with the stress and anxiety of COVID-19 social distancing. The purpose of this study is to examine if automated text-messages will improve depression and anxiety symptoms and enhance positive mood. Additionally, the investigators will compare the effectiveness of sending messages on a random schedule (using a micro-randomized trial design) or sent by a reinforcement learning policy on overall change in depression and anxiety symptoms and daily mood during the 8-week study.

NCT04473599 Depressive Symptoms Anxiety COVID-19 Behavioral: Uniform random message delivery Behavioral: Reinforcement learning message delivery
MeSH:Depression

Primary Outcomes

Description: Patient Health Questionnaire 9 item (PHQ-9). The PHQ-9 has scores from 0 to 27. Higher scores mean a worse outcome.

Measure: Depression scores

Time: Change from baseline to 8 week follow-up

Description: General Anxiety Disorder 7 item (GAD-7). The GAD-7 has scores from 0 to 21. Higher scores mean a worse outcome.

Measure: Anxiety scores

Time: Change from baseline to 8 week follow-up

Secondary Outcomes

Description: The self-reported mood rating 3 hours after receiving a message. The score is from 0-9. A higher mood rating indicates a better outcome.

Measure: Self reported mood ratings

Time: 8 weeks


No related HPO nodes (Using clinical trials)