CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

Schirmer Test IWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)

Name (Synonyms) Correlation
drug1198 Information Wiki 1.00
drug2937 oral polio vaccine + information Wiki 1.00

Correlated MeSH Terms (1)

Name (Synonyms) Correlation
D003231 Conjunctivitis NIH 0.71

Correlated HPO Terms (1)

Name (Synonyms) Correlation
HP:0000509 Conjunctivitis HPO 0.71

There is one clinical trial.

Clinical Trials

1 Tear Fluid miRNA Analysis in Sars-Cov2 Conjunctivitis

The aim of this study is to assess the virus RNA, and miRNA levels related to viral infection, and inflammatory response in tears of hospitalized patients with a diagnosis of COVID-19 with and without conjunctivitis and to correlate them with clinical condition. Tears will be collected by using Schirmer Test I, a non invasive painless test which can be performed at the patient's bed. Tears will be collected on the graduated paper strips pulling the lower lid gently downward for 5 minutes. Following, the strip will be placed in a 2.0 mL Eppendorf tube and stored at −80◦C (or - 20°C)

NCT04346160 COVID Conjunctivitis Diagnostic Test: Schirmer Test I
MeSH:Conjunctivitis
HPO:Conjunctivitis

Primary Outcomes

Description: - to asses virus RNA and miRNA levels in tears

Measure: virus molecular analysis

Time: 2 weeks

Description: - to asses inflammatory response molecules

Measure: host molecular analysis

Time: 2 weeks

Secondary Outcomes

Description: To analyze the prevalence of conjunctivitis in patients with a diagnosis of COVID-19 and the assessment of the predictive value of conjunctivitis in the development of the COVID-19 disease (or in developing respiratory distress forms-ARDS).

Measure: Epidemiologic data

Time: 2 weeks

Related HPO nodes (Using clinical trials)

HP:0000509: Conjunctivitis
Genes 117
VPS33A XPC IL12A MPLKIP LBR BLNK PSMB9 WIPF1 CD79A XPA FGFR2 TP63 CD19 CD19 MEFV IL12A-AS1 SAMD9 DNASE1L3 LMNA NLRP1 IL10 IGHM CD79B GTF2H5 WAS AIRE STAT4 TP63 DDB2 IL23R GJB2 ERF HLCS ERCC3 ERAP1 UROS BTK IGSF3 CCR1 LRBA TNFRSF13C UROS NLRP3 DKC1 BTD AEBP1 KLRC4 RNF125 BTNL2 FOXC2 COL7A1 HLA-B PLG MMP1 RAG1 ERCC2 NOD2 NLRP3 CD79B IGLL1 GTF2E2 RNF113A TNFRSF13B ICOS GSN CR2 HLA-B TARS1 GNAS B2M RAG2 GNAS STX16 NLRP3 ERCC6 BTK TNFRSF1A C4A IKZF1 UBAC2 ERCC2 MBTPS2 SCN9A PSMB8 FERMT1 FOXC2 TCF3 TFRC PSMB4 PIK3R1 SLC39A4 AP1B1 FOXE3 GJB6 HLA-DRB1 MPLKIP IARS2 IGHM BTK TKT ZMPSTE24 FGFR2 NLRP3 ERCC2 LRRC8A BTD MAB21L1 TP63 TLR4 POLH MBTPS2 USB1 GNAS ICOS NLRP3 GATA1 FAS
Protein Mutations 0
SNP 0