Name (Synonyms) | Correlation | |
---|---|---|
D020181 | Sleep Apnea, Obstructive NIH | 0.58 |
D012891 | Sleep Apnea, NIH | 0.50 |
D040921 | Stress Disorders, Traumatic NIH | 0.22 |
D013313 | Stress Disorders, Post-Traumatic NIH | 0.20 |
Name (Synonyms) | Correlation | |
---|---|---|
HP:0002870 | Obstructive sleep apnea HPO | 0.58 |
HP:0010535 | Sleep apnea HPO | 0.50 |
There is one clinical trial.
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke. Obesity, a growing problem for Americans and Veterans alike, is the greatest risk factor for the development of OSA. Male gender and smoking, other OSA risk factors, are common in Veterans. Given the high comorbidity of these risk factors in Veterans, OSA presents a significant health burden to Veterans. The investigators' prior work provides evidence that OSA occurs in up to 69% of Vietnam-era Veterans with PTSD. OSA is easily treated; however, 15-30% of OSA patients are non-compliant with continuous positive airway pressure (CPAP), the standard OSA treatment. The proposed research aims to facilitate adherence to CPAP treatment by testing a novel cognitive-behavioral therapy intervention in Veterans with PTSD. If successful, it may represent an approach that could be applied to the rehabilitation of other chronic conditions with similar barriers to care.
Description: The CPAP machine will measure the number of hours that the CPAP mask is on the participant's face and in use.
Measure: Time in hours of "mask-on" CPAP usage per night Time: 1 yearDescription: Effect of CBT on Self-reported Everyday Activities, Mood and Quality of Life. The investigators hypothesize that after initiating CPAP treatment, Veterans in the CBT-OSA group will report more improvement in the ease of performing everyday activities compared to that reported by those in the Education group.
Measure: Functional Outcomes of Sleep Questionnaire (FOSQ) Time: 1 yearDescription: Effect of CBT on Cognitive Outcomes. The CBT-OSA group will have better cognitive outcomes than the Education group over time. The California Verbal Learning Test-II, Delayed Recall Score is the cognitive outcome measure.
Measure: California Verbal Learning Test, Second Edition (CVLT-II) Time: 1 yearDescription: Effect of CBT on PTSD. The CBT-OSA group will have fewer PTSD symptoms than the Education group over time. The PTSD Checklist for DSM-5 (PCL-5) will be the PTSD outcome measure.
Measure: PTSD Checklist for DSM-5 (PCL-5) Time: 1 year